ArticleGMS Interdisciplinary plastic and reconstructive surgery DGPW2015
Reconstructive surgery in immunocompromised patients: evaluation and therapy.
Article in GMS Interdisciplinary plastic and reconstructive surgery DGPW, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Mythbusters in Microsurgery: Evaluating Evidence and Debunking Dogma-A Practical Review: Part I.Plastic and reconstructive surgery. Global open · 2026Review
- Application of a paste-type acellular dermal matrix for coverage of chronic ulcerative wounds.Archives of plastic surgery · 2019Article
- Wound Healing Problems in the Mouth.Frontiers in physiology · 2016Review
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn increasing number of patients undergoing reconstructive surgery are immunocompromised due to different reasons and different medical treatments. Some of the used immunosuppressive drugs may affect the process of wound healing and thereby, impair the long-term success of surgical treatment. Therefore, this retrospective analysis aimed at the evaluation of the perioperative treatment and surgical outcome of immunocompromised patients undergoing different reconstructive procedures.
methodsA retrospective review was performed of 8 immunocompromised patients with different primary diseases who needed reconstructive surgery: 2 patients with non-Hodgkin lymphoma, 1 patient with an acute myeloid leukemia, 1 patient with colitis ulcerosa, 1 patient with liver cirrhosis, 1 patient with chronic polyarthritis, and 2 patients with malignant melanoma.
resultsIn 7 of our 8 presented cases, multiple operations with wound debridements have been necessary to optimize the granulation of the wound bed before reconstructive surgery. 3 out of these 7 patients required further operations due to wound dehiscence or necrosis, with 2 of them as a result of increased immunosuppressive therapy. 5 out of 8 patients needed no further surgical treatment.
conclusionsBoth the perioperative drug therapy and the reconstructive surgery concept need to be determined carefully in each individual case of the immunocompromised patients. Thus, the appropriate point in time of operation to achieve the best possible wound healing as well as the complexity of the procedure will require the consideration of a 'less is more' strategy in selected cases.
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