Evidence map›Paper›PMID 26734478›Full record

ArticleIranian Red Crescent medical journal2015

Delayed Diagnosis of Hypothyroidism in Children: Report of 3 Cases.

Nosrat Ghaemi, Sepideh Bagheri, Saghi Elmi, Saber Mohammadzade Rezaee, Sam Elmi, Reza Erfani Sayyar

Open access · greenAbstract readCase Reports
In one paragraph

Article in Iranian Red Crescent medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nosrat GhaemiDepartment of Pediatrics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.
Sepideh BagheriDepartment of Pediatrics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.
Saghi ElmiDepartment of Pediatrics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.
Saber Mohammadzade RezaeeDepartment of Pediatrics, School of Medicine, Birjand University of Medical Sciences, Birjand, IR Iran.
Sam ElmiDepartment of Pediatrics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.
Reza Erfani SayyarDepartment of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.
Mashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHypothyroidism is the most common endocrine disorder in children and presented with various sign and symptoms; its diagnosis needs a high index of suspicion. CASE PRESENTATION: We report 3 cases with unusual presentations of hypothyroidism and with delay in diagnosis that referred to Pediatric Endocrine Outpatient Clinic in Mashhad University of Medical Sciences, Mashhad, Iran with different clinical manifestations. They had decreased Thyroxin (T4) and increased thyroid stimulating hormone (TSH) levels. One case had mental retardation and deafness, but the other two cases had normal neurodevelopment. Some additional interesting findings were as follows: short stature, delayed bone age, teeth eruption impairment, hair loss, anemia and hypercholesterolemia, persistent and long-term constipation that had led to several abdominal surgeries. After a year of hormonal replacement therapy, their growth parameters and hematological values improved.

conclusionsWe recommend thyroid hormonal evaluation for any children with short stature, especially with delayed bone age, in order to detect and treat hypothyroidism at the right time. It seems that more attention to pediatric growth is necessary.

Indexed as

Bone AgeConstipationDeafnessHypothyroidismMental RetardationShort Stature

Identifiers

PMID26734478
PMCPMC4698140
OpenAlexW2180072240

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.