ReviewBeilstein journal of organic chemistry2015
Synthesis of bi- and bis-1,2,3-triazoles by copper-catalyzed Huisgen cycloaddition: A family of valuable products by click chemistry.
Review in Beilstein journal of organic chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- ShimNetV2-RM Neural Network for Post-Acquisition Correction of Spectral Lineshapes in NMR Reaction Monitoring.Magnetic resonance in chemistry : MRC · 2026Article
- One-Pot Synthesis of 1,2,3-Triazole-Phthalimide Derivatives as Potential Antibacterial: Molecular Docking, DFT and ADMET Studies.Journal of fluorescence · 2026Article
- Mechanochemical Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC).The Journal of organic chemistry · 2026Review
- Review
- Direct Organocatalytic Chemoselective Synthesis of Pharmaceutically Active 1,2,3-Triazoles and 4,5'-Bitriazoles.ACS organic & inorganic Au · 2024Article
- One-pot nucleophilic substitution-double click reactions of biazides leading to functionalized bis(1,2,3-triazole) derivatives.Beilstein journal of organic chemistry · 2023Article
- 5-Formyltriazoles as Valuable Starting Materials for Unsymmetrically Substituted Bi-1,2,3-Triazoles.Frontiers in chemistry · 2020Article
- A Suitable Functionalization of Nitroindazoles with Triazolyl and Pyrazolyl Moieties via Cycloaddition Reactions.Molecules (Basel, Switzerland) · 2019Article
- Azide-alkyne cycloaddition reactions in waterRSC advances · 2018Article
- Novel Triazole Hybrids of Betulin: Synthesis and Biological Activity Profile.Molecules (Basel, Switzerland) · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Cu(I)-catalyzed azide-alkyne cycloaddition reaction, also known as click chemistry, has become a useful tool for the facile formation of 1,2,3-triazoles. Specifically, the utility of this reaction has been demonstrated by the synthesis of structurally diverse bi- and bis-1,2,3-triazoles. The present review focuses on the synthesis of such bi- and bistriazoles and the importance of using copper-promoted click chemistry (CuAAC) for such transformations. In addition, the application of bitriazoles and the related CuAAAC reaction in different fields, including medicinal chemistry, coordination chemistry, biochemistry, and supramolecular chemistry, have been highlighted.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.