ReviewBeilstein journal of organic chemistry2015
Recent highlights in biosynthesis research using stable isotopes.
Review in Beilstein journal of organic chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Inverse stable isotopic labeling for natural product characterization and discovery.Natural product reports · 2026Review
- An IntegratedACS catalysis · 2026Article
- MARTS-DB: a database of mechanisms and reactions of terpene synthases.BMC bioinformatics · 2025Article
- Engineering terpene synthases and their substrates for the biocatalytic production of terpene natural products and analogues.Chemical communications (Cambridge, England) · 2025Review
- IMA fungus · 2025Review
- Detection of Inverse Stable Isotopic Labeling in Untargeted Metabolomic Data.Analytical chemistry · 2024Article
- The use of nitrogen-15 in microbial natural product discovery and biosynthetic characterization.Frontiers in microbiology · 2023Review
- CPExtract, a Software Tool for the Automated Tracer-Based Pathway Specific Screening of Secondary Metabolites in LC-HRMS Data.Analytical chemistry · 2022Article
- A general, versatile and divergent synthesis of selectively deuterated amines.Chemical science · 2021Article
- Selective oxidation of alcohol-RSC advances · 2021Article
- Methylotroph Quorum Sensing Signal Identification by Inverse Stable Isotopic Labeling.ACS chemical biology · 2021Article
- Quantitative analysis of seven plant hormones in Lotus japonicus using standard addition method.PloS one · 2021Article
- P(III)/P(V)-Catalyzed Methylamination of Arylboronic Acids and Esters: Reductive C-N Coupling with Nitromethane as a Methylamine Surrogate.Journal of the American Chemical Society · 2020Article
- Tracking isotopically labeled oxidants using boronate-based redox probes.The Journal of biological chemistry · 2020Article
- Mechanistic Studies on Trichoacorenol Synthase from Amycolatopsis benzoatilytica.Chembiochem : a European journal of chemical biology · 2020Article
- Fabclavine diversity inBeilstein journal of organic chemistry · 2020Article
- Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase.Journal of lipid research · 2019Article
- Methyl Jasmonate Changes the Composition and Distribution Rather than the Concentration of Defence Compounds: a Study on Pyrrolizidine Alkaloids.Journal of chemical ecology · 2019Article
- Detailed Mechanistic Study of the Non-enzymatic Formation of the Discoipyrrole Family of Natural Products.Journal of the American Chemical Society · 2016Article
- A detailed view on 1,8-cineol biosynthesis byBeilstein journal of organic chemistry · 2016Article
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2 authors.
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Abstract
The long and successful history of isotopic labeling experiments within natural products research has both changed and deepened our understanding of biosynthesis. As demonstrated in this article, the usage of isotopes is not at all old-fashioned, but continues to give important insights into biosynthetic pathways of secondary metabolites. This review with 85 cited references is structured by separate discussions of compounds from different classes including polyketides, non-ribosomal peptides, their hybrids, terpenoids, and aromatic compounds formed via the shikimate pathway. The text does not aim at a comprehensive overview, but instead a selection of recent important examples of isotope usage within biosynthetic studies is presented, with a special emphasis on mechanistic surprises.
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