ArticleBeilstein journal of organic chemistry2015
Diversity-oriented synthesis of analogues of the novel macrocyclic peptide FR-225497 through late stage functionalization.
Article in Beilstein journal of organic chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Discovery of Benzopyrrolizidines as Promising Antigiardiasic Agents.Frontiers in cellular and infection microbiology · 2021Article
- α,ß-Didehydrosuberoylanilide hydroxamic acid (DDSAHA) as precursor and possible analogue of the anticancer drug SAHA.Beilstein journal of organic chemistry · 2019Article
- Cross metathesis-mediated synthesis of hydroxamic acid derivatives.Beilstein journal of organic chemistry · 2018Article
- Synthesis of 2-aminosuberic acid derivatives as components of some histone deacetylase inhibiting cyclic tetrapeptides.Beilstein journal of organic chemistry · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
A concise synthetic approach to a class of biologically interesting cyclic tetrapeptides is reported which involves a late-stage functionalization of a macrocyclic scaffold through cross metathesis in an attempt to create diversity. The utility of this protocol is demonstrated through the preparation of three structural analogues of the important naturally occurring histone deacetylase inhibitor FR-225497.
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Registered trials
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