ArticleFrontiers in plant science2015
Universal Stress Protein Exhibits a Redox-Dependent Chaperone Function in Arabidopsis and Enhances Plant Tolerance to Heat Shock and Oxidative Stress.
Article in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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55 citing papers in PubMed, 102 citations in OpenAlex.
- Germination-Related Universal Stress Protein (GRUSP) Is Involved in Abscisic Acid Responses During Imbibition and Early Post-Germination Growth ofInternational journal of molecular sciences · 2026Article
- USP Gene Network Modulation and Osmoprotection Define Salt Resilience in Chenopodium quinoa Genotypes.Scientific reports · 2026Article
- Integrative cross-study analysis of maize microarray datasets identifies key abiotic stress-responsive genes, highlighting ZmOSM34 and ZmANAH.Scientific reports · 2026Article
- Unveiling the early defense response dynamics in grapevines against Plasmopara viticola by single-cell transcriptomics.Genome biology · 2026Article
- Genome-wide identification and analysis of the Universal Stress Protein (USP) family in pepper (Frontiers in plant science · 2026Article
- Genome landscape of the universal stress protein gene family in lettuce and expression profile in response to heat stress.BMC plant biology · 2025Article
- Major genic factors influencing nitrogen response in rice revealed through in-silico characterization and expression dynamics of a set of novel candidate genes.Molecular biology reports · 2025Article
- Evolutionary and Functional Insights into Rice Universal Stress Proteins in Response to Abiotic Stresses.Biology · 2025Article
- Genome-wide identification and characterization of the universal stress protein (USP) gene family in the AC genome of Brassica species.Genetica · 2025Article
- Exploring the structural landscape of universal stress proteins in Archaea.World journal of microbiology & biotechnology · 2025Review
- Identification of key modules and genes in response to high-temperature stress in Platostoma palustre based on WGCNA.BMC plant biology · 2025Article
- WGCNA analysis reveals hub genes in the Hemarthria compressa roots in response to waterlogging stress.Scientific reports · 2025Article
- Plant-derived recombinant macromolecular PAP-IgG Fc as a novel prostate cancer vaccine candidate eliciting robust immune responses.Transgenic research · 2025Article
- The Evolution and expression analysis of USP gene family inFrontiers in plant science · 2025Article
- Plant-derived EpCAM-Fc fusion proteins induce in vivo immune response to produce IgGs inhibiting invasion and migration of colorectal cancer cells.Plant cell reports · 2024Article
- Molecular, Structural, and Functional Diversity of Universal Stress Proteins (USPs) in Bacteria, Plants, and Their Biotechnological Applications.The protein journal · 2024Review
- Investigation of heat stress responses and adaptation mechanisms by integrative metabolome and transcriptome analysis in tea plants (Camellia sinensis).Scientific reports · 2024Article
- Characterization and gene expression analysis reveal universal stress proteins respond to abiotic stress in Gossypium hirsutum.BMC genomics · 2024Article
- Genome-Wide Identification and Expression Profiling of Potato (International journal of molecular sciences · 2024Article
- Genome-Wide Analysis of the Universal Stress Protein Gene Family in Blueberry and Their Transcriptional Responses to UV-B Irradiation and Abscisic Acid.International journal of molecular sciences · 2023Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although a wide range of physiological information on Universal Stress Proteins (USPs) is available from many organisms, their biochemical, and molecular functions remain unidentified. The biochemical function of AtUSP (At3g53990) from Arabidopsis thaliana was therefore investigated. Plants over-expressing AtUSP showed a strong resistance to heat shock and oxidative stress, compared with wild-type and Atusp knock-out plants, confirming the crucial role of AtUSP in stress tolerance. AtUSP was present in a variety of structures including monomers, dimers, trimers, and oligomeric complexes, and switched in response to external stresses from low molecular weight (LMW) species to high molecular weight (HMW) complexes. AtUSP exhibited a strong chaperone function under stress conditions in particular, and this activity was significantly increased by heat treatment. Chaperone activity of AtUSP was critically regulated by the redox status of cells and accompanied by structural changes to the protein. Over-expression of AtUSP conferred a strong tolerance to heat shock and oxidative stress upon Arabidopsis, primarily via its chaperone function.
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