ReviewFrontiers in microbiology2015
Potential Use of Phenolic Acids as Anti-Candida Agents: A Review.
Review in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed.
- Unexplored Bioactive, Antioxidant, Antimicrobial, and Nematicidal Potential of the Flowers, Leaves, and Roots of 'Yellow Chicory' (Pharmaceuticals (Basel, Switzerland) · 2026Article
- Organ-Specific Distribution of Bioactive Compounds inAntioxidants (Basel, Switzerland) · 2026Article
- Terroir-driven phenolic chemotypes and antioxidant/antimicrobial activities of Beldia (Cannabis sativa L.) seed extracts.Journal of cannabis research · 2026Article
- The effectiveness of Annona muricata for improving induced oral candidiasis in gamma-irradiated rats.BMC complementary medicine and therapies · 2026Article
- Nutritional Composition, Phenolic Profile, Antioxidant, and Antimicrobial Activity of Bilberry, Lingonberry, and Blueberry Cultivars.International journal of food science · 2026Article
- Natural product based approaches to overcomeFrontiers in antibiotics · 2026Review
- Sargassum incisifolium and Ulva spp metabolites activity and their molecular dynamics simulation against Fusarium oxysporum 14-alpha-demethylase.Biotechnology reports (Amsterdam, Netherlands) · 2025Article
- Article
- Exploration of Bioactive Components, Nutritional Properties, Antioxidant, Antimicrobial and Antihemolytic Potential of Different Parts ofFood science & nutrition · 2025Article
- Vaginal mycobiome characteristics and therapeutic strategies in vulvovaginal candidiasis (VVC): differentiating pathogenic species and microecological features for stratified treatment.Clinical microbiology reviews · 2025Review
- Multi-Omics Analysis Revealed the Accumulation of Flavonoids and Shift of Fungal Community Structure Caused by Tea Grafting (Plants (Basel, Switzerland) · 2025Article
- Bioactive Blend of Extracts of Molle Leaf and Rica-Rica Flowers To Enhance the Shelf Life of Reduced-Calorie Artisanal Cayote Jam.Plant foods for human nutrition (Dordrecht, Netherlands) · 2025Article
- Anacardiaceae Family: Effect of Isolated Compounds and Other Identified Phytochemicals Against Clinically RelevantAntibiotics (Basel, Switzerland) · 2025Review
- Proteomics analysis revealed the activation and suppression of different host defense components challenged with mango leaf spot pathogen Alternaria alternata.BMC plant biology · 2025Article
- Comparison of Secondary Metabolite Extraction Methods inMetabolites · 2025Article
- Medicinal plants: bioactive compounds, biological activities, combating multidrug-resistant microorganisms, and human health benefits - a comprehensive review.Frontiers in immunology · 2025Review
- Mustard Meal Extract as an Alternative to Zinc Oxide for Protecting the Intestinal Barrier AgainstInternational journal of molecular sciences · 2024Article
- Qualitative Profiling, Antioxidant and Antimicrobial Activities of Polar and Nonpolar Basil Extracts.Foods (Basel, Switzerland) · 2024Article
- Article
- Anticandidal Activity of Various Probiotic Lactobacillus Strains and Their Efficacy Enhanced by Prebiotic Supplementation.Current microbiology · 2024Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There has been a sharp rise in the occurrence of Candida infections and associated mortality over the last few years, due to the growing body of immunocompromised population. Limited number of currently available antifungal agents, undesirable side effects and toxicity, as well as emergence of resistant strains pose a considerable clinical challenge for the treatment of candidiasis. Therefore, molecules that derived from natural sources exhibiting considerable antifungal properties are a promising source for the development of novel anti-candidal therapy. Phenolic compounds isolated from natural sources possess antifungal properties of interest. Particularly, phenolic acids have shown promising in vitro and in vivo activity against Candida species. However, studies on their mechanism of action alone or in synergism with known antifungals are still scarce. This review attempts to discuss the potential use, proposed mechanisms of action and limitations of the phenolic acids in anti-candidal therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.