Evidence map›Paper›PMID 26733847›Full record

ArticleFrontiers in human neuroscience2015

Effect of Paired-Pulse Electrical Stimulation on the Activity of Cortical Circuits.

Kei Saito, Hideaki Onishi, Shota Miyaguchi, Shinichi Kotan, Shuhei Fujimoto

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Using Cutaneous Receptor Vibration to Uncover the Effect of Transcranial Magnetic Stimulation (TMS) on Motor Cortical Excitability.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kei SaitoDepartment of Physical Therapy, Niigata University of Health and WelfareNiigata, Japan; Institute for Human Movement and Medical Sciences, Niigata University of Health and WelfareNiigata, Japan.
Hideaki OnishiDepartment of Physical Therapy, Niigata University of Health and WelfareNiigata, Japan; Institute for Human Movement and Medical Sciences, Niigata University of Health and WelfareNiigata, Japan.
Shota MiyaguchiInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare Niigata, Japan.
Shinichi KotanInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare Niigata, Japan.
Shuhei FujimotoGraduate School of Medicine, Kyoto University Kyoto, Japan.
Niigata University of Health and Welfare · JPKyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe investigated the transient effect of short-duration paired-pulse electrical stimulation (ppES) on corticospinal excitability and the after-effect of long-duration ppES on excitability, short-latency afferent inhibition (SAI), and afferent facilitation (AF).

methodsA total of 28 healthy subjects participated in two different experiments. In Experiment 1, motor-evoked potentials (MEPs) were measured in the abductor pollicis brevis (APB) and abductor digiti minimi (ADM) muscles before and immediately after short-duration ppES (5 s) at various inter-pulse intervals (2, 3, 4, 5, 6, 7, 10, 15, 20, and 30 ms). In Experiment 2, MEPs, SAI, and AF were measured before, immediately, and 20 and 40 min after long-duration ppES (20 min, inter-pulse interval of 5 and 15 ms) and peripheral electrical stimulation (20 min, 10 and 20 Hz).

resultsShort-duration ppES with inter-pulse intervals of 5 and 20 ms significantly increased MEP measured in APB but not in ADM. Long-duration ppES with an inter-pulse interval of 5 ms significantly decreased SAI but not MEPs in APB. In contrast, long-duration ppES did not affect ADM.

conclusionThe afferent inputs induced by ppES-5 ms were effective for transiently increasing MEP and sustaining SAI reduction.

Indexed as

corticospinal excitabilitycorticospinal pathwaysmotor cortexperipheral electrical stimulationshort-latency afferent inhibition

Identifiers

PMID26733847
PMCPMC4687412
OpenAlexW2305785059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.