ReviewFrontiers in neuroscience2015
Investigating Human Neurovascular Coupling Using Functional Neuroimaging: A Critical Review of Dynamic Models.
Review in Frontiers in neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
73 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Associations between neurovascular coupling and cerebral small vessel disease: A systematic review and meta-analysis.European stroke journal · 2023Pooled it
- Processing of fMRI-related anxiety and bi-directional information flow between prefrontal cortex and brain stem.Scientific reports · 2021Trial
- Non-invasive Computational Techniques for Diagnosing Myocardial Ischemia: Challenges and Future of FFRAnnals of biomedical engineering · 2026Review
- Systems biology analysis of vasodynamics in mouse cerebral arterioles during resting state and functional hyperemia.PLoS computational biology · 2026Article
- Adiponectin deficiency drives cerebrovascular dysfunction and synergizes with amyloid-β to exacerbate alzheimer's pathology.Alzheimer's research & therapy · 2026Article
- Spatial evolution in temporal dynamics of hemodynamic response function in human superior colliculi with ultra-high-resolution MRI at 9.4T.Frontiers in neuroscience · 2026Article
- Assessment of cortical activity, functional connectivity, and neuroplasticity in cerebral palsy using functional near-infrared spectroscopy: A scoping review.Developmental medicine and child neurology · 2025Article
- Direct crosstalk between adult human retinas as suggested by interocular transfer of neurovascular coupling through photic stimulation.Scientific reports · 2025Article
- Ocular diagnostics and occipital neurovascular coupling in ocular hypertension and open angle glaucoma.Frontiers in neuroscience · 2025Article
- Reorganization of the sensorimotor cortex in patients with Ph-negative myeloproliferative neoplasms according to functional MRI.Frontiers in neuroscience · 2025Article
- Neurovascular coupling dysfunction in encephalopathy: pathophysiological advances and clinical implications.Frontiers in neurology · 2025Review
- Stimulus type and duration affect magnitude and evolution of flicker-induced hyperemia measured by laser speckle flowgraphy at the optic disc and peripapillary vessels.Scientific reports · 2024Article
- Traces of EEG-fMRI coupling reveals neurovascular dynamics on sleep inertia.Scientific reports · 2024Article
- Dynamic retinal vessel analysis: flickering a light into the brain.Frontiers in aging neuroscience · 2024Review
- Spatiotemporal features of neurovascular (un)coupling with stimulus-induced activity and hypercapnia challenge in cerebral cortex and olfactory bulb.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Cerebral multi-autoregulation model based enhanced external counterpulsation treatment planning for cerebral ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Emerging trends in the development of flexible optrode arrays for electrophysiology.APL bioengineering · 2023Review
- Hemodynamic timing in resting-state and breathing-task BOLD fMRI.NeuroImage · 2023Article
- Scalable, modular continuous wave functional near-infrared spectroscopy system (Spotlight).Journal of biomedical optics · 2023Article
- Applications of near-infrared spectroscopy in neurocritical care.Neurophotonics · 2023Review
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanisms that link a transient neural activity to the corresponding increase of cerebral blood flow (CBF) are termed neurovascular coupling (NVC). They are possibly impaired at early stages of small vessel or neurodegenerative diseases. Investigation of NVC in humans has been made possible with the development of various neuroimaging techniques based on variations of local hemodynamics during neural activity. Specific dynamic models are currently used for interpreting these data that can include biophysical parameters related to NVC. After a brief review of the current knowledge about possible mechanisms acting in NVC we selected seven models with explicit integration of NVC found in the literature. All these models were described using the same procedure. We compared their physiological assumptions, mathematical formalism, and validation. In particular, we pointed out their strong differences in terms of complexity. Finally, we discussed their validity and their potential applications. These models may provide key information to investigate various aspects of NVC in human pathology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.