Evidence map›Paper›PMID 26732879›Full record

ArticleHead & face medicine2016

Sinusitis and oroantral fistula in patients with bisphosphonate-associated necrosis of the maxilla.

Pit Jacob Voss, Gustavo Vargas Soto, Rainer Schmelzeisen, Kiwako Izumi, Andres Stricker, Gido Bittermann, Philipp Poxleitner

Open access · goldAbstract read
In one paragraph

Article in Head & face medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. CD34 and CD105 Microvessels in Resected Bone Specimen May Implicate Wound Healing in MRONJ.International journal of environmental research and public health · 2021
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Pit Jacob VossDepartment of Oral and Maxillofacial Surgery, Regional Plastic Surgery, Medical Center - University of Freiburg , Hugstetter Str. 55, 79106, Freiburg im Breisgau, Germany. pit.voss@uniklinik-freiburg.de.
Gustavo Vargas SotoDepartment of Oral and Maxillofacial Surgery, Hospital San Juan de Dios, Universidad Latina, San José, Costa Rica.
Rainer SchmelzeisenDepartment of Oral and Maxillofacial Surgery, Regional Plastic Surgery, Medical Center - University of Freiburg , Hugstetter Str. 55, 79106, Freiburg im Breisgau, Germany.
Kiwako IzumiDepartment of Oral and Maxillofacial Surgery, Fukuoka Dental College, Fukuoka, Japan.
Andres StrickerDepartment of Oral and Maxillofacial Surgery, Regional Plastic Surgery, Medical Center - University of Freiburg , Hugstetter Str. 55, 79106, Freiburg im Breisgau, Germany.
Gido BittermannDepartment of Oral and Maxillofacial Surgery, Regional Plastic Surgery, Medical Center - University of Freiburg , Hugstetter Str. 55, 79106, Freiburg im Breisgau, Germany.
Philipp PoxleitnerDepartment of Oral and Maxillofacial Surgery, Regional Plastic Surgery, Medical Center - University of Freiburg , Hugstetter Str. 55, 79106, Freiburg im Breisgau, Germany.
University of Freiburg · DEFukuoka Dental College · JPLatin University of Costa Rica · CRUniversity Medical Center Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of bisphosphonate related necrosis of the jaw has become clinical routine. While approximately two thirds of the lesions are in the mandible, one third is located in the maxilla. In 40-50 % of maxillary necrosis the maxillary sinus is involved, leading to maxillary sinusitis and oro-antral communications.

methodsThis retrospective single center study includes all patients with diagnosis of BP-ONJ of the maxilla and concomitant maxillary sinusitis. The information collected includes age, gender, primary disease, bisphosphonate intake, involving type of bisphosphonate, route of administration and duration of BP treatment previous to surgical treatment and treatment outcome.

resultsA total of 12 patients fulfill the criteria of the diagnosis of maxillary sinusitis associated to maxillary necrosis, of which 6 Patients showed purulent sinusitis. All patients underwent surgical treatment with complete resection of the affected bone and a multilayer wound closure. A recurrence appeared in one patient with open bone and no sign of sinusitis and was treated conservatively.

conclusionsPurulent maxillary Sinusitis is a common complication of bisphosphonate-related necrosis of the maxilla. The surgical technique described can be suggested for the treatment of these patients.

Indexed as

AgedAged, 80 and overBisphosphonate-Associated Osteonecrosis of the JawFemaleHumansMaleMaxillaMiddle AgedRetrospective StudiesSinusitisSurgical FlapsTreatment Outcome

Identifiers

PMID26732879
PMCPMC4702393
OpenAlexW2224149856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.