ArticleFrontiers in microbiology2015
Oleanolic Acid Induces the Type III Secretion System of Ralstonia solanacearum.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Article
- Apoplast Metabolomics Profiling Reveals Nitrogen-Dependent Modulation of Plant-Pathogen Interactions.Molecular plant pathology · 2025Article
- Deciphering metabolite signalling between plant roots and soil pathogens to design resistance.BMC plant biology · 2025Review
- Gatifloxacin hydrochloride confers broad-spectrum antibacterial activity against phytopathogenic bacteria.Frontiers in microbiology · 2024Article
- Bacterial tolerance to host-exuded specialized metabolites structures the maize root microbiome.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Antimicrobial Peptides: The Production of Novel Peptide-Based Therapeutics in Plant Systems.Life (Basel, Switzerland) · 2023Review
- A screening identifies harmine as a novel antibacterial compound againstFrontiers in microbiology · 2023Article
- Mitigation of tobacco bacteria wilt with microbial degradation of phenolic allelochemicals.Scientific reports · 2022Article
- Silicon Controls Bacterial Wilt Disease in Tomato Plants and Inhibits the Virulence-Related Gene Expression ofInternational journal of molecular sciences · 2022Article
- Preliminary Studies on the Antibacterial Mechanism of a New Plant-Derived Compound, 7-Methoxycoumarin, AgainstFrontiers in microbiology · 2021Article
- Effects of Halophyte Root Exudates and Their Components on Chemotaxis, Biofilm Formation and Colonization of the Halophilic BacteriumMicroorganisms · 2020Article
- The Lifecycle of the Plant Immune System.Critical reviews in plant sciences · 2020Article
- Molecular Mechanisms That Define Redox Balance Function in Pathogen-Host Interactions-Is There a Role for Dietary Bioactive Polyphenols?International journal of molecular sciences · 2019Review
- Involvement of a PadR regulator PrhP on virulence of Ralstonia solanacearum by controlling detoxification of phenolic acids and type III secretion system.Molecular plant pathology · 2019Article
- Fabrication of pH-Sensitive Tetramycin Releasing Gel and Its Antibacterial Bioactivity againstMolecules (Basel, Switzerland) · 2019Article
- Involvement of NpdA, a Putative 2-Nitropropane Dioxygenase, in the T3SS Expression and Full Virulence inFrontiers in microbiology · 2017Article
- Ferulic Acid, But Not All Hydroxycinnamic Acids, Is a Novel T3SS Inducer ofFrontiers in plant science · 2017Article
- Exposure to Umbelliferone ReducesFrontiers in microbiology · 2017Article
- Extract from Maize (Zea mays L.): Antibacterial Activity of DIMBOA and Its Derivatives against Ralstonia solanacearum.Molecules (Basel, Switzerland) · 2016Article
- Evaluation of the Antibacterial Effects and Mechanism of Action of Protocatechualdehyde against Ralstonia solanacearum.Molecules (Basel, Switzerland) · 2016Article
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5 authors.
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Abstract
Ralstonia solanacearum, the causal agent of bacterial wilt, can naturally infect a wide range of host plants. The type III secretion system (T3SS) is a major virulence determinant in this bacterium. Studies have shown that plant-derived compounds are able to inhibit or induce the T3SS in some plant pathogenic bacteria, though no specific T3SS inhibitor or inducer has yet been identified in R. solanacearum. In this study, a total of 50 different compounds were screened and almost half of them (22 of 50) significantly inhibited or induced the T3SS expression of R. solanacearum. Based on the strong induction activity on T3SS, the T3SS inducer oleanolic acid (OA) was chosen for further study. We found that OA induced the expression of T3SS through the HrpG-HrpB pathway. Some type III effector genes were induced in T3SS inducing medium supplemented with OA. In addition, OA targeted only the T3SS and did not affect other virulence determinants. Finally, we observed that induction of T3SS by OA accelerated disease progress on tobacco. Overall our results suggest that plant-derived compounds are an abundant source of R. solanacearum T3SS regulators, which could prove useful as tools to interrogate the regulation of this key virulence pathway.
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