ArticleAddiction biology2017
Activation of the ventral and dorsal striatum during cue reactivity in Internet gaming disorder.
Article in Addiction biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 5 of them syntheses that pooled it.
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Who cites it
61 citing papers in PubMed, 5 syntheses or guidelines pooled it, 186 citations in OpenAlex.
- Neural mechanisms of behavioral addiction: An ALE meta-analysis and MACM analysis.Journal of behavioral addictions · 2025Pooled it
- Structural gray matter differences in Problematic Usage of the Internet: a systematic review and meta-analysis.Molecular psychiatry · 2022Pooled it
- Meta-analysis of structural and functional brain alterations in internet gaming disorder.Frontiers in psychiatry · 2022Pooled it
- Structural and Functional Brain Abnormalities in Internet Gaming Disorder and Attention-Deficit/Hyperactivity Disorder: A Comparative Meta-Analysis.Frontiers in psychiatry · 2021Pooled it
- Cue-reactivity in behavioral addictions: A meta-analysis and methodological considerations.Journal of behavioral addictions · 2018Pooled it
- Pain Catastrophizing Is Associated With Increased Alcohol Cue-Elicited Neural Activity Among Individuals With Alcohol Use Disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022Trial
- Psychophysiological response of individuals with internet gaming disorder to gaming content from social media.Addictive behaviors reports · 2025Article
- Neural Correlates of Resistance to Gaming Desire Induced by Social Media Content.Addiction biology · 2025Article
- Imbalanced goal-directed and habitual control in individuals with internet gaming disorder.Journal of behavioral addictions · 2025Article
- Altered dynamic reconfiguration of brain functional networks during gaming and deprivation in individuals with internet gaming disorder.Journal of behavioral addictions · 2025Article
- Temporal attentional bias to visual game stimuli in Internet gaming disorder.Journal of behavioral addictions · 2025Article
- Gaming disorder: Neural mechanisms and ongoing debates.Journal of behavioral addictions · 2025Review
- Interconnections of screen time with neuroinflammation.Molecular and cellular biochemistry · 2025Review
- Gaming disorder and problematic caffeine consumption in adolescents: a narrative review and public health framework.Frontiers in psychology · 2025Review
- Assessment of Attentional Bias in Internet Gaming Disorder Using the Addiction Stroop Task and Event-Related Potentials.Addiction & health · 2025Article
- Understanding the relationships among adolescents' internet dependence, reward, cognitive control processing, and learning burnout: a network perspective in China.BMC psychiatry · 2024Article
- Biomarkers of Internet Gaming Disorder-A Narrative Review.Journal of clinical medicine · 2024Review
- Compulsivity-related behavioral features of problematic usage of the internet: A scoping review of paradigms, progress, and perspectives.Journal of behavioral addictions · 2024Article
- Appetitive conditioning with pornographic stimuli elicits stronger activation in reward regions than monetary and gaming-related stimuli.Human brain mapping · 2024Article
- Effects of Game-Related Tasks for the Diagnosis and Classification of Gaming Disorder.Biosensors · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
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Abstract
Studies conducted in drug addiction suggest a transition in processing of drug-related cues from the ventral to the dorsal component of the striatum. However, this process has not been studied in a behavioral addiction. Assessment of this process in a non-drug addiction can provide insight into the pathophysiology of both substance and behavioral addictions. Thirty-nine male Internet gaming disorder (IGD) subjects and 23 male matched healthy controls (HCs) participated in functional magnetic resonance imaging during performance of a cue-reactivity task involving alternating presentation of Internet gaming-related stimuli (game cues) and general Internet surfing-related stimuli (control cues). Cue-induced neural activations in the ventral and dorsal striatum (DS) were compared between IGD and HC participants. Associations between cue-reactivity within these regions and cue-induced craving and severity and duration of IGD were also explored. IGD participants exhibited higher cue-induced activations within both the ventral and DS when compared with HCs. Within the IGD group, activity within the left ventral striatum (VS) was correlated negatively with cue-induced craving; positive associations were found between activations within the DS (right putamen, pallidum and left caudate) and duration of IGD. Cue-induced activity within the left putamen was negatively associated with right VS volumes among IGD participants. Consistent with studies in substance addictions, our results suggest that a transition from ventral to dorsal striatal processing may occur among individuals with IGD, a condition without the impact of substance intake.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.