ArticleAngewandte Chemie (International ed. in English)2016
Temporal Control of Gelation and Polymerization Fronts Driven by an Autocatalytic Enzyme Reaction.
Article in Angewandte Chemie (International ed. in English), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Autonomous Spatiotemporal Regulation of Reversible Hydrogel Actuators by Chemical Reaction Networks.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Exploring Emergent Properties in Enzymatic Reaction Networks: Design and Control of Dynamic Functional Systems.Chemical reviews · 2024Review
- Timed Pulses in DNA Strand Displacement Reactions.Journal of the American Chemical Society · 2023Article
- Controlled Annealing in Adaptive Multicomponent Gels.Angewandte Chemie (International ed. in English) · 2023Article
- Photoswitchable gating of non-equilibrium enzymatic feedback in chemically communicating polymersome nanoreactors.Nature chemistry · 2023Article
- Influence of Oxygen on Chemoconvective Patterns in the Iodine Clock Reaction.The journal of physical chemistry. B · 2022Article
- Using Rheology to Understand Transient and Dynamic Gels.Gels (Basel, Switzerland) · 2022Article
- Quantum Dots-Loaded Self-Healing Gels for Versatile Fluorescent Assembly.Nanomaterials (Basel, Switzerland) · 2022Article
- Feedback and Communication in Active Hydrogel Spheres with pH Fronts: Facile Approaches to Grow Soft Hydrogel Structures.Angewandte Chemie (International ed. in English) · 2021Article
- Dissipative operation of pH-responsive DNA-based nanodevices.Chemical science · 2021Article
- Autonomous DNA nanostructures instructed by hierarchically concatenated chemical reaction networks.Nature communications · 2021Article
- Reaction-diffusion hydrogels from urease enzyme particles for patterned coatings.Communications chemistry · 2021Article
- Urea-Urease Reaction in Controlling Properties of Supramolecular Hydrogels: Pros and Cons.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Review
- pH Feedback Lifecycles Programmed by Enzymatic Logic Gates Using Common Foods as Fuels.Angewandte Chemie (International ed. in English) · 2021Article
- Time-programmable pH: decarboxylation of nitroacetic acid allows the time-controlled rising of pH to a definite value.Chemical science · 2021Article
- Autonomous Transient pH Flips Shaped by Layered Compartmentalization of Antagonistic Enzymatic Reactions.Angewandte Chemie (International ed. in English) · 2021Article
- Enzyme-Regulated Healable Polymeric Hydrogels.ACS central science · 2020Review
- Programmable dynamic steady states in ATP-driven nonequilibrium DNA systems.Science advances · 2019Article
- Immobilization adjusted clock reaction in the urea-urease-HRSC advances · 2019Article
- Feedback-Induced Temporal Control of "Breathing" Polymersomes To Create Self-Adaptive Nanoreactors.Journal of the American Chemical Society · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chemical systems that remain kinetically dormant until activated have numerous applications in materials science. Herein we present a method for the control of gelation that exploits an inbuilt switch: the increase in pH after an induction period in the urease-catalyzed hydrolysis of urea was used to trigger the base-catalyzed Michael addition of a water-soluble trithiol to a polyethylene glycol diacrylate. The time to gelation (minutes to hours) was either preset through the initial concentrations or the reaction was initiated locally by a base, thus resulting in polymerization fronts that converted the mixture from a liquid into a gel (ca. 0.1 mm min(-1)). The rate of hydrolytic degradation of the hydrogel depended on the initial concentrations, thus resulting in a gel lifetime of hours to months. In this way, temporal programming of gelation was possible under mild conditions by using the output of an autocatalytic enzyme reaction to drive both the polymerization and subsequent degradation of a hydrogel.
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