Trial reportJournal of clinical hypertension (Greenwich, Conn.)2016
Effect of Intensive Salt-Restriction Education on Clinic, Home, and Ambulatory Blood Pressure Levels in Treated Hypertensive Patients During a 3-Month Education Period.
Trial report in Journal of clinical hypertension (Greenwich, Conn.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06907524 (Community-Based Preventative Cardiometabolic Screening and Health Coaching- A Prospective Study), which is not on this map. Cited by 20 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Community-Based Preventative Cardiometabolic Screening and Health Coaching- A Prospective Study
Who cites it
20 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- An updated network meta-analysis of non-pharmacological interventions for primary hypertension in adults: insights from recent studies.Systematic reviews · 2024Pooled it
- Replacing salt with low-sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women.The Cochrane database of systematic reviews · 2022Pooled it
- Differences of blood pressure measured at clinic versus at home in the morning and in the evening in Europe and Asia: A systematic review and meta-analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2022Pooled it
- Reducing salt intake: a systematic review and meta-analysis of behavior change interventions in adults.Nutrition reviews · 2022Pooled it
- Pooled it
- Blood Pressure Effects of Sodium Reduction: Dose-Response Meta-Analysis of Experimental Studies.Circulation · 2021Pooled it
- Dietary Sodium Intake and Health Indicators: A Systematic Review of Published Literature between January 2015 and December 2019.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- More evidence that salt increases blood pressure and risk of kidney disease from the Science of Salt: A regularly updated systematic review of salt and health outcomes (April-July 2016).Journal of clinical hypertension (Greenwich, Conn.) · 2017Pooled it
- Efficacy of a digital therapeutics system in the management of essential hypertension: the HERB-DH1 pivotal trial.European heart journal · 2021Trial
- Add-On Use of Eplerenone Is Effective for Lowering Home and Ambulatory Blood Pressure in Drug-Resistant Hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2016Trial
- Psychological Determinants of Purchasing Behavior Among Individuals Indifferent to Reduced-Salt Products.Nutrients · 2026Article
- Article
- Monitoring Sodium Intake With a Salt Meter in Hemodialysis Patients.Kidney international reports · 2025Article
- Digital therapeutic for hypertension improves physician-patient communication and clinical inertia: a survey of physicians who implemented CureApp HT in clinical practice.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Dietary intervention for the management of hypertension in Asia.Journal of clinical hypertension (Greenwich, Conn.) · 2021Review
- A multicenter clinical trial to assess the efficacy of the digital therapeutics for essential hypertension: Rationale and design of the HERB-DH1 trial.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Asian management of hypertension: Current status, home blood pressure, and specific concerns in Japan.Journal of clinical hypertension (Greenwich, Conn.) · 2020Review
- Expert panel consensus recommendations for ambulatory blood pressure monitoring in Asia: The HOPE Asia Network.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Impact of the 2017 American College of Cardiology/American Heart Association Blood Pressure Guidelines on the Next Blood Pressure Guidelines in Asia.Current hypertension reports · 2019Review
- Dietary Salt Restriction: How Much Education Is Enough?Journal of clinical hypertension (Greenwich, Conn.) · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The authors tested the hypothesis that low-salt diet education by nutritionists would lower blood pressure (BP) levels in treated hypertensive patients. The amount of urinary salt excretion and clinic, home, and ambulatory BP values at baseline and at 3 months were measured in 95 patients with hypertension. After randomization to a nutritional education group (E group, n=51) or a control group (C group, n=44), the C group received conventional salt-restriction education and the E group received intensive nutritional education aimed at salt restriction to 6 g/d by nutritionists. From baseline to the end of the study, 24-hour urinary sodium excretion was significantly lowered in the E group compared with the C group (6.8±2.9 g/24 h vs 8.6±3.4 g/24 h, P<.01). Morning home systolic BP tended to be lowered in the E group (P=.051), and ambulatory 24-hour systolic BP was significantly lowered in the E group (-4.5±1.3 mm Hg) compared with the C group (2.8±1.3 mm Hg, P<.001). Intensive nutritional education by nutritionists was shown to be effective in lowering BP in treated hypertensive patients.
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