Evidence map›Paper›PMID 26732120›Full record

Trial reportTrials2016

Effectiveness of an individualized program of muscular strength and endurance with aerobic training for improving germ cell cancer-related fatigue in men undergoing chemotherapy: EFICATEST study protocol for a randomized controlled trial.

Antonio Ignacio Cuesta-Vargas, Francisco Carabantes, Zaira Caracuel, Inmaculada Conejo, Emilio Alba

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02433197 nacompletednot on this map

Effectiveness of an Individualized Program of Muscular Strength and Endurance Program With Aerobic Training for Improving Germ Cell Cancer Related Fatigue in Men Undergoing Chemotherapy

TypeinterventionalSponsorUniversity of MalagaRan2015Enrolled20ConditionsTesticular Germ Cell CancerArmsAerobic program
NCT03879096 nacompletednot on this map

Clinical and Functional Variables in the Assessment of Oncology Patient

TypeinterventionalSponsorUniversity of MalagaRan2016 to 2023Enrolled120ConditionsCancer, Metastatic, Cancer, SurvivorshipArmsTherapeutic Exercise and Education
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Implementation of a Standard Care Program of Therapeutic Exercise in Metastatic Breast Cancer Patients.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Antonio Ignacio Cuesta-VargasDepartment of Physiotherapy, Faculty of Health Sciences, Instituto de Investigacion de Biomedicina de Malaga (IBIMA), Universidad de Malaga, Málaga, Spain. acuesta.var@gmail.com.
Francisco CarabantesDepartment of Medical Oncology, Carlos Haya Regional University Hospital, Málaga, Spain. fcarabantes@hotmail.com.
Zaira CaracuelDepartment of Cellular Biology, Genetics and Physiology, Faculty of Sciences, Universidad de Malaga, Málaga, Spain. Zacari@hcs.es.
Inmaculada ConejoDepartment of Physiotherapy, Faculty of Health Sciences, Instituto de Investigacion de Biomedicina de Malaga (IBIMA), Universidad de Malaga, Málaga, Spain. inmaconejo@gmail.com.
Emilio AlbaDepartment of Medical Oncology, Carlos Haya Regional University Hospital, Málaga, Spain. ealbac@uma.es.
Hospital Regional Universitario de Málaga · ESInstituto de Investigación Biomédica de Málaga · ESUniversidad de Málaga · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with testicular germ cell cancer (GCC) have a high cure rate; however, cancer-related fatigue is the most common complication among patients with GCC undergoing treatment with chemotherapy. Although exercise is widely recommended, information about the physio-pathological effects of cancer therapy on skeletal muscle is very limited. Our aim is to evaluate the effects of an individualized program of muscular strength and endurance with aerobic training on cancer-related fatigue. METHODS/

designThe present study is a randomized controlled trial comparing an individualized program of muscular strength and endurance with aerobic training compared to a control group. We will conduct this trial in patients undergoing chemotherapy, recruited by the Department of Oncology of Virgen de la Victoria Hospital (Málaga). Patients will be included and evaluated before the first cycle of chemotherapy and assigned randomly to the experimental or control group. Cancer-related fatigue, physical condition and biological samples will be measured at the beginning and at the end of an 8-week intervention by the same evaluator, who will be unaware of the allocation of participants to each group. Furthermore, there will be monitoring for 6 months (24 weeks) after training for all outcome variables. DISCUSSION: This study hopes to offer patients with GCC an individualized exercise program with aerobic training for cancer-related fatigue. Such a scheme, if beneficial, could be implemented successfully within public health.

trial registrationClinicalTrials.gov Identifier: NCT02433197 . Date of registration: 13 April 2015.

Indexed as

Clinical ProtocolsMuscle StrengthPhysical EnduranceAdolescentAdultData Interpretation, StatisticalExerciseFatigueHumansMaleMetabolomicsMiddle AgedNeoplasms, Germ Cell and EmbryonalTesticular Neoplasms

Identifiers

PMID26732120
PMCPMC4702371
OpenAlexW2225898946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.