SynthesisPloS one2016
Economic Evaluation of Interventions for Prevention of Hospital Acquired Infections: A Systematic Review.
Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Fragility index-based robustness assessment of RCT-driven meta-analyses in hospital-acquired infection management.BMC infectious diseases · 2026Pooled it
- Economic Evaluation of a Catheter-Associated Urinary Tract Infection Prevention Program in Nursing Homes.Journal of the American Geriatrics Society · 2018Trial
- Antimicrobial activity of topcoat formulation based on synthesized new cyclodiphosph(V)azane derivatives as a biocide for protective coatings.Scientific reports · 2026Article
- Beyond awareness: evaluating the impact of a hospital-wide, multi-station infection prevention and control (IPC) innovation campaign on core hospital infection control committee (HICC) performance metrics - a pre-post audit study.GMS hygiene and infection control · 2026Article
- Utilization of affordable nanocomposites with outstanding antimicrobial activity in waterborne coatings.Scientific reports · 2025Article
- Nanomaterial-Based Antimicrobial Coating for Biomedical Implants: New Age Solution for Biofilm-Associated Infections.ACS omega · 2022Review
- Engineering biomaterials to prevent post-operative infection and fibrosis.Drug delivery and translational research · 2021Review
- Nonventilator hospital-acquired pneumonia: A call to action.Infection control and hospital epidemiology · 2021Article
- Association of Postoperative Infections After Fractures With Long-term Income Among Adults.JAMA network open · 2021Article
- Word Entropy-Based Approach to Detect Highly Variable Genetic Markers for Bacterial Genotyping.Frontiers in microbiology · 2021Article
- Economic Analysis of the Prevention and Control of Nosocomial Infections: Research Protocol.Frontiers in public health · 2021Article
- Are Invasive Procedures and a Longer Hospital Stay Increasing the Risk of Healthcare-Associated Infections among the Admitted Patients at Hiwot Fana Specialized University Hospital, Eastern Ethiopia?Advances in preventive medicine · 2020Article
- Hand hygiene compliance and environmental contamination with gram-negative bacilli in a rural hospital in Madarounfa, Niger.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2019Article
- Cost-effectiveness of interventions to reduce the risk of healthcare-acquired infections in middle-income countries: A systematic review.Journal of infection prevention · 2019Review
- Healthcare-associated pneumonia in acute care hospitals in European Union/European Economic Area countries: an analysis of data from a point prevalence survey, 2011 to 2012.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018Article
- Economic evaluations and their use in infection prevention and control: a narrative review.Antimicrobial resistance and infection control · 2018Review
- An observational case study of hospital associated infections in a critical care unit in Astana, Kazakhstan.Antimicrobial resistance and infection control · 2018Observational
- Article
- Utilization of a central venous catheter insertion care bundle in Taiwan: A cross-sectional analysis of the National Health Insurance Research Database.Tzu chi medical journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis systematic review sought to assess the costs and benefits of interventions preventing hospital-acquired infections and to evaluate methodological and reporting quality.
methodsWe systematically searched Medline via PubMed and the National Health Service Economic Evaluation Database from 2009 to 2014. We included quasi-experimental and randomized trails published in English or German evaluating the economic impact of interventions preventing the four most frequent hospital-acquired infections (urinary tract infections, surgical wound infections, pneumonia, and primary bloodstream infections). Characteristics and results of the included articles were extracted using a standardized data collection form. Study and reporting quality were evaluated using SIGN and CHEERS checklists. All costs were adjusted to 2013 US$. Savings-to-cost ratios and difference values with interquartile ranges (IQRs) per month were calculated, and the effects of study characteristics on the cost-benefit results were analyzed.
resultsOur search returned 2067 articles, of which 27 met the inclusion criteria. The median savings-to-cost ratio across all studies reporting both costs and savings values was US $7.0 (IQR 4.2-30.9), and the median net global saving was US $13,179 (IQR 5,106-65,850) per month. The studies' reporting quality was low. Only 14 articles reported more than half of CHEERS items appropriately. Similarly, an assessment of methodological quality found that only four studies (14.8%) were considered high quality.
conclusionsPrevention programs for hospital acquired infections have very positive cost-benefit ratios. Improved reporting quality in health economics publications is required.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.