Evidence map›Paper›PMID 26730984›Full record

ArticleSubstance abuse

Alcohol screening scores and the risk of intensive care unit admission and hospital readmission.

Brendan J Clark, Anna D Rubinsky, P Michael Ho, David H Au, Laura J Chavez, Marc Moss, Katharine A Bradley

Open access · greenAbstract read
In one paragraph

Article in Substance abuse. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

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  14. Epidemiology and Outcomes in Critically Ill Patients with Human Immunodeficiency Virus Infection in the Era of Combination Antiretroviral Therapy.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Brendan J Clarka Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado , Aurora , Colorado , USA.
Anna D Rubinskyb Center of Excellence for Substance Abuse Treatment and Education , Department of Veterans Affairs Puget Sound Health Care System , Seattle , Washington , USA.
P Michael Hod Division of Cardiology, Department of Medicine, Denver VA Medical Center , Denver , Colorado , USA.
David H Auc Health Services Research and Development , Department of Veterans Affairs Puget Sound Health Care System , Seattle , Washington , USA.
Laura J Chavezc Health Services Research and Development , Department of Veterans Affairs Puget Sound Health Care System , Seattle , Washington , USA.
Marc Mossa Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado , Aurora , Colorado , USA.
Katharine A Bradleyb Center of Excellence for Substance Abuse Treatment and Education , Department of Veterans Affairs Puget Sound Health Care System , Seattle , Washington , USA.
Health Services Research & Development · USUniversity of Colorado Anschutz Medical Campus · USVA Puget Sound Health Care System · USDenver VA Medical Center · US

Funding

Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
Patient Oriented Research Program in ALI/ARFK24HL089223 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MOSS, MARC · 2007 to 2016
$1.4M
Tailored Screening, Brief Intervention, and Referral to Treatment for Medical IntK23AA021814 · NIAAA · UNIVERSITY OF COLORADO DENVER · PI CLARK, BRENDAN JAMES · 2014 to 2017
$688k
Unhealthy Drinking in Older Adults: 30-day Readmissions and Emergency CareR36HS022800 · AHRQ · UNIVERSITY OF WASHINGTON · PI CHAVEZ, LAURA JOHNSON · 2013 to 2013
$42k
AHRQ HHS R36 HS022800HSRD VA SDR 02-237NCATS NIH HHS UL1 TR001082NHLBI NIH HHS K24 HL089223NIAAA NIH HHS K23 AA021814
6 · The paper itself

Abstract

backgroundThe association between alcohol misuse and the need for intensive care unit admission as well as hospital readmission among those discharged from the hospital following a critical illness is unclear. This study sought to determine whether alcohol misuse was associated with (1) admission to an intensive care unit (ICU) among a cohort of patients receiving outpatient care and (2) hospital readmission among those discharged from the hospital following critical illness.

methodsThis was a retrospective cohort study conducted with data from 24 Veterans Affairs (VA) health care facilities between 2004 and 2007. Scores on the Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) questionnaire were used to identify patients with past-year abstinence, lower-risk alcohol use, moderate alcohol misuse, or severe alcohol misuse. The primary outcome was admission to a VA intensive care unit within the year following administration of the AUDIT-C. In an analysis focused on patients discharged from the ICU, the 2 main outcomes were hospital readmission within 1 year and within 30 days.

resultsAmong 486,115 veterans receiving outpatient care, the adjusted probability of ICU admission within 1 year was 2.0% (95% confidence interval [CI]: 1.7%-2.3%) for abstinent patients, 1.6% (95% CI: 1.3%-1.8%) for patients with lower-risk alcohol use, 1.8% (1.4%-2.3%) for patients with moderate alcohol misuse, and 2.5% (2.0%-2.9%) for patients with severe alcohol misuse. Among the 9,030 patients discharged from an ICU, the adjusted probability of hospital readmission within 1 year was 48% (46%-49%) in abstinent patients, 44% (42%-45%) in patients with lower-risk alcohol use, 42% (39%-45%) in patients with moderate alcohol misuse, and 55% (49%-60%) in patients with severe alcohol misuse.

conclusionsAlcohol misuse may represent a modifiable risk factor for a cycle of ICU admission and subsequent hospital readmission.

Indexed as

AdolescentAdultAgedAged, 80 and overAlcoholismCritical CareFemaleHospitalizationHumansIntensive Care UnitsMaleMiddle AgedOutpatientsPatient ReadmissionRetrospective StudiesUnited StatesAlcohol abusealcohol consumptionalcohol-related disordershealth care utilizationintensive care unitspatient readmission

Identifiers

PMID26730984
PMCPMC5669033
OpenAlexW2260322776

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.