ArticlePediatric exercise science2016
Cardiopulmonary Exercise Testing in Children and Adolescents with High Body Mass Index.
Article in Pediatric exercise science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 43 citations in OpenAlex.
- Sex Differences in the Impact of Body Composition and Bone Mineral Content on Cardiopulmonary Performance in Elite Youth Water Polo Athletes.Sports (Basel, Switzerland) · 2026Article
- Correlation between cardiorespiratory fitness and body composition in individuals with different glucose metabolism statuses.Frontiers in endocrinology · 2026Article
- New applications of cardiopulmonary exercise testing parameters characterize age-related changes in exercise performance during adolescence.Frontiers in cardiovascular medicine · 2026Article
- Physical Activity and Exercise Prescription and Guidelines for Adolescents.Advances in experimental medicine and biology · 2026Review
- Ventilatory response and dyspnea on exertion in children with obesity and respiratory symptoms.Respiratory physiology & neurobiology · 2025Article
- Myocardial function, mechanics and work by echocardiography in adolescents with severe obesity.Cardiovascular endocrinology & metabolism · 2024Article
- Cardiorespiratory fitness and circadian rhythms in adolescents: a pilot study.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Association between cardiorespiratory fitness level and insulin resistance in adolescents with various obesity categories.World journal of diabetes · 2023Article
- Evaluation of Muscle Oxygen Dynamics in Children's Gait and Its Relationship with the Physiological Cost Index.Healthcare (Basel, Switzerland) · 2023Article
- Health-Related Physical Fitness in Adolescents from Spain, Estonia and Iceland: A Cross-Sectional, Quantitative Study.Sports (Basel, Switzerland) · 2022Article
- Heart rate and gas exchange dynamic responses to multiple brief exercise bouts (MBEB) in early- and late-pubertal boys and girls.Physiological reports · 2022Article
- A Combined Analysis of Peak and Submaximal Exercise Parameters in Delineating Underlying Mechanisms of Sex Differences in Healthy Adolescents.Pediatric cardiology · 2022Article
- Pediatric youth who have obesity have high rates of adult criminal behavior and low rates of homeownership.SAGE open medicine · 2022Article
- Relating cardiorespiratory responses to work rate during incremental ramp exercise on treadmill in children and adolescents: sex and age differences.European journal of applied physiology · 2021Article
- Cardiopulmonary Capacity in Overweight and Obese Children and Adolescents: A Cross-Sectional Study.Frontiers in physiology · 2021Article
- Evolution of the Habits of Physical Activity and Television Viewing in Spanish Children and Pre-Adolescents between 1997 and 2017.International journal of environmental research and public health · 2020Observational
- Validation of the Activity Preference Assessment: a tool for quantifying children's implicit preferences for sedentary and physical activities.The international journal of behavioral nutrition and physical activity · 2020Article
- External dead space explains sex-differences in the ventilatory response to submaximal exercise in children with and without obesity.Respiratory physiology & neurobiology · 2020Article
- A Pilot Study of Cardiorespiratory Fitness, Adiposity, and Cardiometabolic Health in Youth With Overweight and Obesity.Pediatric exercise science · 2020Article
- Exercise-associated prevention of adult cardiovascular disease in children and adolescents: monocytes, molecular mechanisms, and a call for discovery.Pediatric research · 2020Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Consensus has yet to be achieved on whether obesity is inexorably tied to poor fitness. We tested the hypothesis that appropriate reference of cardiopulmonary exercise testing (CPET) variables to lean body mass (LBM) would eliminate differences in fitness between high-BMI (≥ 95th percentile, n = 72, 50% female) and normal-BMI (< 85th percentile, n = 142, 49% female), otherwise-healthy children and adolescents typically seen when referencing body weight. We measured body composition with dual x-ray absorptiometry (DXA) and CPET variables from cycle ergometry using both peak values and submaximal exercise slopes (peak VO2, ΔVO2/ΔHR, ΔWR/ΔHR, ΔVO2/ΔWR, and ΔVE/ΔVCO2). In contrast to our hypothesis, referencing to LBM tended to lessen, but did not eliminate, the differences (peak VO2 [p < .004] and ΔVO2/ΔHR [p < .02]) in males and females; ΔWR/ΔHR differed between the two groups in females (p = .041) but not males (p = .1). The mean percent predicted values for all CPET variables were below 100% in the high-BMI group. The pattern of CPET abnormalities suggested a pervasive impairment of O2 delivery in the high-BMI group (ΔVO2/ΔWR was in fact highest in normal-BMI males). Tailoring lifestyle interventions to the specific fitness capabilities of each child (personalized exercise medicine) may be one of the ways to stem what has been an intractable epidemic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.