Evidence map›Paper›PMID 26730321›Full record

ReviewJournal of ophthalmic & vision research

Extracellular Matrix Components Regulate Cellular Polarity and Tissue Structure in the Developing and Mature Retina.

Shweta Varshney, Dale D Hunter, William J Brunken

Open access · goldAbstract readReview
In one paragraph

Review in Journal of ophthalmic & vision research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Retinal glia in myopia: current understanding and future directions.Frontiers in cell and developmental biology · 2024
    Review
  10. Defect ofInternational journal of molecular sciences · 2023
    Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Laminin β2 Chain Regulates Retinal Progenitor Cell Mitotic Spindle Orientation via Dystroglycan.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
  18. Architecture in 3D cell culture: An essential feature for in vitro toxicology.Toxicology in vitro : an international journal published in association with BIBRA · 2017
    Review
  19. Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shweta VarshneyDepartment of Ophthalmology and Cell Biology, SUNY Downstate Medical Center, Brooklyn NY, USA; SUNY Eye Institute, NY, USA.
Dale D HunterDepartment of Ophthalmology and Cell Biology, SUNY Downstate Medical Center, Brooklyn NY, USA; SUNY Eye Institute, NY, USA; Department of Ophthalmology and Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA.
William J BrunkenDepartment of Ophthalmology and Cell Biology, SUNY Downstate Medical Center, Brooklyn NY, USA; SUNY Eye Institute, NY, USA; Department of Ophthalmology and Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA.
SUNY Downstate Health Sciences University · US

Funding

Role of Extracellular Matrix in Retinal Development and DiseaseR01EY012676 · NEI · UPSTATE MEDICAL UNIVERSITY · PI BRUNKEN, WILLIAM J · 2000 to 2021
$6.9M
NEI NIH HHS R01 EY012676
6 · The paper itself

Abstract

While genetic networks and other intrinsic mechanisms regulate much of retinal development, interactions with the extracellular environment shape these networks and modify their output. The present review has focused on the role of one family of extracellular matrix molecules and their signaling pathways in retinal development. In addition to their effects on the developing retina, laminins play a role in maintaining Müller cell polarity and compartmentalization, thereby contributing to retinal homeostasis. This article which is intended for the clinical audience, reviews the fundamentals of retinal development, extracellular matrix organization and the role of laminins in retinal development. The role of laminin in cortical development is also briefly discussed.

Indexed as

DystroglycanopathyLamininMüller CellRetinal Progenitor Cell

Identifiers

PMID26730321
PMCPMC4687269
OpenAlexW2278953657

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.