Evidence map›Paper›PMID 26730187›Full record

ReviewInternational journal of nanomedicine2016

Dendrimers as tunable vectors of drug delivery systems and biomedical and ocular applications.

Marina Kalomiraki, Kyriaki Thermos, Nikos A Chaniotakis

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
8.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 174 citations in OpenAlex.

  1. Pooled it
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  7. Recent advances and future challenges in nanosystems for ocular drug delivery.The Journal of pharmacology and experimental therapeutics · 2025
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  16. An Overview of Recent Developments in the Management of Burn Injuries.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Marina KalomirakiLaboratory of Analytical Chemistry, Department of Chemistry, University of Crete Voutes, Heraklion, Greece.
Kyriaki ThermosDepartment of Pharmacology, School of Medicine, University of Crete Voutes, Heraklion, Greece.
Nikos A ChaniotakisLaboratory of Analytical Chemistry, Department of Chemistry, University of Crete Voutes, Heraklion, Greece.
Czech Academy of Sciences, Institute of Analytical Chemistry · CZUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendrimers are large polymeric structures with nanosize dimensions (1-10 nm) and unique physicochemical properties. The major advantage of dendrimers compared with linear polymers is their spherical-shaped structure. During synthesis, the size and shape of the dendrimer can be customized and controlled, so the finished macromolecule will have a specific "architecture" and terminal groups. These characteristics will determine its suitability for drug delivery, diagnostic imaging, and as a genetic material carrier. This review will focus initially on the unique properties of dendrimers and their use in biomedical applications, as antibacterial, antitumor, and diagnostic agents. Subsequently, emphasis will be given to their use in drug delivery for ocular diseases.

Indexed as

Administration, OralAnti-Bacterial AgentsAntineoplastic AgentsDendrimersDiagnostic Uses of ChemicalsDrug Delivery SystemsDrug InteractionsEye DiseasesGene Transfer TechniquesHumansNanomedicinePolymersAnti-Bacterial AgentsAntineoplastic AgentsDendrimersDiagnostic Uses of ChemicalsPolymersdiagnostic agentencapsulationmacromoleculenanoparticlesocular diseases

Identifiers

PMID26730187
PMCPMC4694674
OpenAlexW2199446042

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.