ArticleThe American journal of gastroenterology2016
Prevalence of Adult Celiac Disease in India: Regional Variations and Associations.
Article in The American journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 3 of them syntheses that pooled it.
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Who cites it
65 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Diagnostic Accuracy of IgA Anti-Transglutaminase Assessed by Chemiluminescence: A Systematic Review and Meta-Analysis.Nutrients · 2024Pooled it
- Prevalence of celiac disease in low and high risk population in Asia-Pacific region: a systematic review and meta-analysis.Scientific reports · 2021Pooled it
- Screening for Celiac Disease in Irritable Bowel Syndrome: An Updated Systematic Review and Meta-analysis.The American journal of gastroenterology · 2017Pooled it
- Celiac Disease: A Comprehensive Review of Epidemiology, Pathogenesis, and Therapeutic Strategies.Digestive diseases and sciences · 2026Review
- Pancytopenia as the Initial Presentation of Celiac Disease.ACG case reports journal · 2026Article
- Clinical and Histopathological Profile of Adults with Celiac Disease at Diagnosis and on a Gluten-Free Diet: A Cross-Sectional Observational Study.Clinics and practice · 2026Article
- Associations of non-HLA gene polymorphisms with celiac disease in India.Scientific reports · 2026Article
- Role of Routine Duodenal Biopsy in Patients with Unexplained Iron Deficiency Anemia in Areas of Low Prevalence of Celiac Disease.Annals of African medicine · 2026Article
- From gluten to therapeutics: molecular mechanisms of celiac disease and emerging alternatives to the gluten-free diet.Frontiers in pharmacology · 2026Review
- Prevalence of acute reactions to gluten contamination of the diet in children with celiac disease.Frontiers in pediatrics · 2025Article
- Computational analysis of human gut microbial prolyl oligopeptidases (POPs) reveal candidate genes as therapeutics for celiac disease.Scientific reports · 2024Article
- Recent Trends in Seroprevalence of Celiac Disease at a Tertiary Care Center.Journal of pharmacy & bioallied sciences · 2024Article
- Celiac Disease in Children: A 2023 Update.Indian journal of pediatrics · 2024Review
- Article
- From an understanding of etiopathogenesis to novel therapies-what is new in the treatment of celiac disease?Frontiers in pharmacology · 2024Review
- Clinical and demographic comparison of celiac disease diagnosed during adulthoodJGH open : an open access journal of gastroenterology and hepatology · 2023Article
- Prevalence of markers of beta cell autoimmunity and thyroid disease in children with coeliac disease.BMC pediatrics · 2023Article
- Quantitative Morphometry and Machine Learning Model to Explore Duodenal and Rectal Mucosal Tissue of Children with Environmental Enteric Dysfunction.The American journal of tropical medicine and hygiene · 2023Article
- An Asian perspective on irritable bowel syndrome.Intestinal research · 2023Review
- Clinical profile of patients with seronegative celiac disease.Gastroenterology and hepatology from bed to bench · 2023Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
20 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAlthough celiac disease (CeD) affects 1% of people in the northern part of India, it is believed to be uncommon in the southern and northeastern parts because of significant differences in dietary pattern and ethnicity. We estimated the prevalence of CeD in these three populations. In a subset, we also investigated differences in the prevalence of HLA-DQ 2/8 allelotype and dietary grain consumption.
methodsA total of 23,331 healthy adults were sampled from three regions of India-northern (n=6207), northeastern (n=8149), and southern (n=8973)-and screened for CeD using IgA anti-tissue transglutaminase antibody. Positive tests were reconfirmed using a second ELISA. CeD was diagnosed if the second test was positive and these participants were further investigated. A subsample of participants was tested for HLA-DQ2/-DQ8 and underwent detailed dietary evaluation.
resultsAge-adjusted prevalence of celiac autoantibodies was 1.23% in northern, 0.87% in northeastern, and 0.10% in southern India (P<0.0001). Prevalence of CeD and latent CeD, respectively, was 8.53/1,000 and 3.70/1,000 in northern, 4.66/1,000 and 3.92/1,000 in northeastern, and 0.11/1,000 and 1.22/1,000 in the southern part. The population prevalence of genes determining HLA-DQ2 and/or -DQ8 expression was 38.1% in northern, 31.4% in northeastern, and 36.4% in southern India. Mean daily wheat intake was highest in northern (455 g) compared with northeastern (37 g) or southern part (25 g), whereas daily rice intake showed an inverse pattern.
conclusionsCeD and latent CeD were most prevalent in northern India and were the least in southern India. The prevalence correlated with wheat intake and did not reflect differences in the genetic background.
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