ReviewNutrients2016
Negative, Null and Beneficial Effects of Drinking Water on Energy Intake, Energy Expenditure, Fat Oxidation and Weight Change in Randomized Trials: A Qualitative Review.
Review in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04737629 (Understanding the Effects of Herbs on Attention, Coordination, and Taste), which is not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Understanding the Effects of Herbs on Attention, Coordination, and Taste
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Narrative Review of Hydration and Selected Health Outcomes in the General Population.Nutrients · 2019Pooled it
- Prevention and Therapy of Type 2 Diabetes-What Is the Potential of Daily Water Intake and Its Mineral Nutrients?Nutrients · 2017Pooled it
- The impact of a water promotion and access intervention on elementary school students in the presence of food insecurity.Public health nutrition · 2024Trial
- Effect of acute hypohydration on glycemic regulation in healthy adults: a randomized crossover trial.Journal of applied physiology (Bethesda, Md. : 1985) · 2019Trial
- Water and Energy Turnover in Chinese Young Adults: A Doubly Labeled Water Study of Metabolic Coupling.Nutrients · 2026Observational
- Unraveling the Enigma of Post-sleeve Differential Liquid Tolerance: A Time-Resolved MRI Study.Obesity surgery · 2025Article
- Water intake, hydration, and weight management: the glass is half-full!Physiology & behavior · 2025Review
- Association between water intake and abdominal obesity: the Korea National Health and Nutrition Examination Survey 2019-2021.Korean journal of family medicine · 2025Article
- Hydration and health at ages 40-70 years in Salzburg Austria is associated with a median total water intake over 40 mL/kg including at least 1 L/d plain drinking water.Frontiers in public health · 2025Article
- Drinking water instead of apple juice or no drink results in greater odds of 4 to 7 co-occurring protective oral health factors within the hour.Frontiers in nutrition · 2025Article
- Article
- Association of plain water intake with risk of all-cause and cause-specific mortality in individuals with non-alcoholic fatty liver disease or metabolic dysfunction-associated steatotic liver disease.Frontiers in nutrition · 2024Article
- Bariatric Surgery in Obesity: Metabolic Quality Analysis and Comparison of Surgical Options.Advances in experimental medicine and biology · 2024Review
- Use and Acceptance of Drinking Fountains: A Pilot Study in Two Secondary Schools in Dortmund, Germany.Children (Basel, Switzerland) · 2023Article
- Current Hydration Habits: The Disregarded Factor for the Development of Renal and Cardiometabolic Diseases.Nutrients · 2022Review
- Water Security and Nutrition: Current Knowledge and Research Opportunities.Advances in nutrition (Bethesda, Md.) · 2021Review
- Higher plain water intake is related to lower newly diagnosed nonalcoholic fatty liver disease risk: a population-based study.European journal of clinical nutrition · 2021Article
- Sensory Circumventricular Organs, Neuroendocrine Control, and Metabolic Regulation.Metabolites · 2021Review
- Effects of diet, habitual water intake and increased hydration on body fluid volumes and urinary analysis of renal fluid retention in healthy volunteers.European journal of nutrition · 2021Article
- A cluster-randomized controlled trial of an elementary school drinking water access and promotion intervention: Rationale, study design, and protocol.Contemporary clinical trials · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drinking water has heterogeneous effects on energy intake (EI), energy expenditure (EE), fat oxidation (FO) and weight change in randomized controlled trials (RCTs) involving adults and/or children. The aim of this qualitative review of RCTs was to identify conditions associated with negative, null and beneficial effects of drinking water on EI, EE, FO and weight, to generate hypotheses about ways to optimize drinking water interventions for weight management. RCT conditions that are associated with negative or null effects of drinking water on EI, EE and/or FO in the short term are associated with negative or null effects on weight over the longer term. RCT conditions that are associated with lower EI, increased EE and/or increased FO in the short term are associated with less weight gain or greater weight loss over time. Drinking water instead of caloric beverages decreases EI when food intake is ad libitum. Drinking water increases EE in metabolically-inflexible, obese individuals. Drinking water increases FO when blood carbohydrate and/or insulin concentrations are not elevated and when it is consumed instead of caloric beverages or in volumes that alter hydration status. Further research is needed to confirm the observed associations and to determine if/what specific conditions optimize drinking water interventions for weight management.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.