ArticleThe journal of nutrition, health & aging2016
Association of Proton Pump Inhibitor Use with Recurrent Falls and Risk of Fractures in Older Women: A Study of Medication Use in Older Fallers.
Article in The journal of nutrition, health & aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Associations between polypharmacy and potentially inappropriate medications with risk of falls among the elderly in Saudi Arabia.BMC geriatrics · 2023Article
- Proton-pump inhibitor use amongst patients with severe hypomagnesemia.Frontiers in pharmacology · 2023Article
- Proton Pump Inhibitors and Bone Health: An Update Narrative Review.International journal of molecular sciences · 2022Review
- Article
- Accuracy of Tools to Differentiate Single From Recurrent Fallers Pre-Frail Older Women.Frontiers in public health · 2022Article
- Utilization of potentially inappropriate medication and risk of adverse drug events among older adults with chronic renal insufficiency: a population-wide cohort study.BMC geriatrics · 2021Article
- Acid-Suppressive Drugs and Risk of Fracture in Children and Young Adults: A Meta-Analysis of Observational Studies.Frontiers in pharmacology · 2021Review
- Helicobacter pylori Related Diseases and Osteoporotic Fractures (Narrative Review).Journal of clinical medicine · 2020Review
- Adverse Effects of Proton Pump Inhibitors-Evidence and Plausibility.International journal of molecular sciences · 2019Review
- Insights into Effects/Risks of Chronic Hypergastrinemia and Lifelong PPI Treatment in Man Based on Studies of Patients with Zollinger-Ellison Syndrome.International journal of molecular sciences · 2019Review
- Prevalence of potentially inappropriate medications in older adults in Argentina using Beers criteria and the IFAsPIAM List.International journal of clinical pharmacy · 2019Observational
- Adverse bone effects of medications used to treat non-skeletal disorders.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Review
- Proton Pump Inhibitors and the Risk for Fracture at Specific Sites: Data Mining of the FDA Adverse Event Reporting System.Scientific reports · 2017Article
- Potentially inappropriate medications in hospitalized older patients: a cross-sectional study using the Beers 2015 criteria versus the 2012 criteria.Clinical interventions in aging · 2017Article
- Proton pump inhibitors and fracture: they impair bone quality and increase fall risk?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Article
- Multidisciplinary Consensus for Rationalizing the Use of Acid Suppressants in Children and Adults: CONFOR.Euroasian journal of hepato-gastroenterologyReview
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo examine the association between Proton pump inhibitors (PPIs) use and falls and fractures.
designA cross-sectional study. SETTING AND
participants400 female patients aged 70 years or older who were consecutively admitted to the Trauma Center Meidling, Vienna, after a fall and who required hospital admission.
methodsWe quantified the strength of the associations between PPI use and falls, and between PPI use and fractures, using a logistic regression.
resultsuse of PPIs was significantly associated with risk of recurrent falls (OR 1.92, 95% CI = 1.05 - 3.50, p = 0.04) as well as with risk of a fracture (OR 2.15, 95% CI 1.10 - 4.21, p = 0.03).
conclusionsIn conclusion, our results provide further evidence that PPI use may increase risk of falls and fractures in older women and highlight the need for clinicians to reassess the original indication and the need for continuation of PPIs on a regular basis.
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