Evidence map›Paper›PMID 26728766›Full record

Trial reportThe American journal of tropical medicine and hygiene2016

Sustained Uptake of a Hospital-Based Handwashing with Soap and Water Treatment Intervention (Cholera-Hospital-Based Intervention for 7 Days [CHoBI7]): A Randomized Controlled Trial.

Christine Marie George, Danielle S Jung, K M Saif-Ur-Rahman, Shirajum Monira, David A Sack, Mahamud-ur Rashid, Md Toslim Mahmud, Munshi Mustafiz, Zillur Rahman, Sazzadul Islam Bhuyian and 9 more

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  5. Risk Factors for Household Transmission ofThe American journal of tropical medicine and hygiene · 2017
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  12. Contextual Determinants of General Household Hygiene Conditions in Rural Indonesia.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 2 countries.

Christine Marie GeorgeJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh cmgeorge@jhsph.edu.
Danielle S JungJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
K M Saif-Ur-RahmanJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Shirajum MoniraJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
David A SackJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Mahamud-ur RashidJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Md Toslim MahmudJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Munshi MustafizJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Zillur RahmanJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Sazzadul Islam BhuyianJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Peter J WinchJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Elli LeontsiniJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Jamie PerinJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Farzana BegumJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Fatema ZohuraJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Shwapon BiswasJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Tahmina ParvinJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
R Bradley SackJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Munirul AlamJohns Hopkins University, Baltimore, Maryland; International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Johns Hopkins University · USInternational Centre for Diarrhoeal Disease Research · BD

Funding

EPIDEMIOLOGY &ECOLOGY OF VIBRIO CHOLERAE IN BANGLADESHR01AI039129 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SACK, DAVID A · 1996 to 2014
$15.2M
Identifying Transmission Routes for Cholera among Household Contacts of Cases K01AI110526 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GEORGE, CHRISTINE MARIE · 2015 to 2017
$410k
NIAID NIH HHS K01 AI110526NIAID NIH HHS R01 AI039129
6 · The paper itself

Abstract

Diarrhea is the second leading cause of death in children under 5 years of age globally. The time patients and caregivers spend at a health facility for severe diarrhea presents the opportunity to deliver water, sanitation, and hygiene (WASH) interventions. We recently developed Cholera-Hospital-Based Intervention for 7 days (CHoBI7), a 1-week hospital-based handwashing with soap and water treatment intervention, for household members of cholera patients. To investigate if this intervention could lead to sustained WASH practices, we conducted a follow-up evaluation of 196 intervention household members and 205 control household members enrolled in a randomized controlled trial of the CHoBI7 intervention 6 to 12 months post-intervention. Compared with the control arm, the intervention arm had four times higher odds of household members' handwashing with soap at a key time during 5-hour structured observation (odds ratio [OR]: 4.71, 95% confidence interval [CI]: 2.61, 8.49) (18% versus 50%) and a 41% reduction in households in the World Health Organization very high-risk category for stored drinking water (OR: 0.38, 95% CI: 0.15, 0.96) (58% versus 34%) 6 to 12 months post-intervention. Furthemore, 71% of observed handwashing with soap events in the intervention arm involved the preparation and use of soapy water, which was promoted during the intervention, compared to 9% of control households. These findings demonstrate that the hospital-based CHoBI7 intervention can lead to significant increases in handwashing with soap practices and improved stored drinking water quality 6 to 12 months post-intervention.

Indexed as

Hand DisinfectionHospitalsSoapsAdolescentAdultAgedAged, 80 and overBangladeshChildChild, PreschoolCholeraDiarrheaDrinking WaterFamily CharacteristicsFemaleHumansDrinking WaterSoaps

Identifiers

PMID26728766
PMCPMC4751953
OpenAlexW2222021309

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.