ArticleMolecular psychiatry2016
Impact of videogame play on the brain's microstructural properties: cross-sectional and longitudinal analyses.
Article in Molecular psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07004036 (The Effects Of Occupation-Based Self-Regulation Program On Sensory Processing, Executive Functions and Occupational Performance In Preschool Children With Screen Addiction), which is not on this map. Cited by 41 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects Of Occupation-Based Self-Regulation Program On Sensory Processing, Executive Functions and Occupational Performance In Preschool Children With Screen Addiction
Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The intervention effect of physical and mental exercise on young adults internet addiction disorder: a systematic review and Bayesian model analysis.Frontiers in public health · 2025Pooled it
- Neuropsychological Deficits in Disordered Screen Use Behaviours: A Systematic Review and Meta-analysis.Neuropsychology review · 2024Pooled it
- Impacts of technology on children's health: a systematic review.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2022Pooled it
- Succeeding in deactivating: associations of hair zinc levels with functional and structural neural mechanisms.Scientific reports · 2020Trial
- Intelligent monitoring-based screen exposure patterns and neurodevelopmental outcomes in preschool children.European journal of pediatrics · 2026Article
- Association of screen time with attention-deficit/hyperactivity disorder symptoms and their development: the mediating role of brain structure.Translational psychiatry · 2025Article
- The Impact of Open-Skill Exercises and E-Sports on Cognitive Function: A Narrative Review of Their Role in Preventing Cognitive Decline and Dementia.Brain sciences · 2025Review
- Single video games improve cognitive functioning in college students: evidence from behavioral and fNIRS assessments.Frontiers in psychiatry · 2025Article
- Long-term impact of digital media on brain development in children.Scientific reports · 2024Article
- Association between gaming disorder and regional homogeneity in highly involved male adult gamers: A pilot resting-state fMRI study.Brain and behavior · 2023Article
- Screen Media Use Affects Subcortical Structures, Resting-State Functional Connectivity, and Mental Health Problems in Early Adolescence.Brain sciences · 2023Article
- Brain structural covariation linked to screen media activity and externalizing behaviors in children.Journal of behavioral addictions · 2022Article
- The Psychosocial Well-Being of Young Video-Gamer Children: A Comparison Study.Turkish archives of pediatrics · 2022Article
- Effects of Diastolic Blood Pressure on Brain Structures and Cognitive Functions in Middle and Old Ages: Longitudinal Analyses.Nutrients · 2022Article
- Effects of Body Mass Index on Brain Structures in the Elderly: Longitudinal Analyses.Frontiers in endocrinology · 2022Article
- Lead exposure is associated with functional and microstructural changes in the healthy human brain.Communications biology · 2021Article
- Caudate nucleus volume mediates the link between glutamatergic neurotransmission and problematic smartphone use in youth.Journal of behavioral addictions · 2021Article
- Childhood socioeconomic status is associated with psychometric intelligence and microstructural brain development.Communications biology · 2021Article
- Differences in resting-state functional connectivity according to the level of impulsiveness in patients with internet gaming disorder.Journal of behavioral addictions · 2021Article
- Videogame exposure positively associates with selective attention in a cross-sectional sample of young children.PloS one · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Videogame play (VGP) has been associated with numerous preferred and non-preferred effects. However, the effects of VGP on the development of microstructural properties in children, particularly those associated with negative psychological consequences of VGP, have not been identified to date. The purpose of this study was to investigate this issue through cross-sectional and longitudinal prospective analyses. In the present study of humans, we used the diffusion tensor imaging mean diffusivity (MD) measurement to measure microstructural properties and examined cross-sectional correlations with the amount of VGP in 114 boys and 126 girls. We also assessed correlations between the amount of VGP and longitudinal changes in MD that developed after 3.0±0.3 (s.d.) years in 95 boys and 94 girls. After correcting for confounding factors, we found that the amount of VGP was associated with increased MD in the left middle, inferior and orbital frontal cortex; left pallidum; left putamen; left hippocampus; left caudate; right putamen; right insula; and thalamus in both cross-sectional and longitudinal analyses. Regardless of intelligence quotient type, higher MD in the areas of the left thalamus, left hippocampus, left putamen, left insula and left Heschl gyrus was associated with lower intelligence. We also confirmed an association between the amount of VGP and decreased verbal intelligence in both cross-sectional and longitudinal analyses. In conclusion, increased VGP is directly or indirectly associated with delayed development of the microstructure in extensive brain regions and verbal intelligence.
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