Evidence map›Paper›PMID 26728489›Full record

ArticleBMC medicine2016

Cancer and fertility preservation: international recommendations from an expert meeting.

Matteo Lambertini, Lucia Del Mastro, Maria C Pescio, Claus Y Andersen, Hatem A Azim, Fedro A Peccatori, Mauro Costa, Alberto Revelli, Francesca Salvagno, Alessandra Gennari and 6 more

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 170 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
170citing papers in PubMed, 18 pooled it
95.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

170 citing papers in PubMed, 18 syntheses or guidelines pooled it, 778 citations in OpenAlex.

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  8. The Educational Program for Healthcare Providers Regarding Fertility Preservation for Cancer Patients: a Systematic Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2021
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  9. ABVD and BEACOPP regimens' effects on fertility in young males with Hodgkin lymphoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
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  11. Reproductive outcomes following a stem cell transplant for a haematological malignancy in female cancer survivors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
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110 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 4 countries.

Matteo LambertiniDepartment of Medical Oncology, U.O. Oncologia Medica 2, IRCCS AOU San Martino - IST, Genoa, Italy. matteo.lambertini85@gmail.com.
Lucia Del MastroDepartment of Medical Oncology, U.O. Sviluppo Terapie Innovative, IRCCS AOU San Martino - IST, Genoa, Italy.
Maria C PescioPhysiopathology of Human Reproduction, IRCCS AOU San Martino - IST, Genoa, Italy.
Claus Y AndersenLaboratory of Reproductive Biology, Section 5712, Juliane Marie Centre for Women, Children and Reproduction, University Hospital of Copenhagen, Copenhagen, Denmark.
Hatem A AzimBrEAST Data Centre, Department of Medicine, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
Fedro A PeccatoriFertility and Procreation Unit, Gynecologic Oncology Department, European Institute of Oncology, Milan, Italy.
Mauro CostaReproductive Medicine Department, International Evangelic Hospital, Genoa, Italy.
Alberto RevelliPhysiopathology of Reproduction and In Vitro Fertilization Unit, S. Anna Hospital, University of Turin, Turin, Italy.
Francesca SalvagnoPhysiopathology of Reproduction and In Vitro Fertilization Unit, S. Anna Hospital, University of Turin, Turin, Italy.
Alessandra GennariDepartment of Medical Oncology, E.O. Galliera, Genoa, Italy.
Filippo M UbaldiGENERA Centre for Reproductive Medicine, Clinica Valle Giulia, Rome, Italy.
Giovanni B La SalaObstetric and Gynecology Department, Azienda Ospedaliera Arcispedale S. Maria Nuova-IRCCS, University of Modena and Reggio Emilia, Reggio Emilia, Italy.
Cristofaro De StefanoChildren and Women Health Department, Physiopathology of Human Reproduction Unit, "San Giuseppe Moscati" Hospital, Avellino, Italy.
W Hamish WallaceDepartment of Haematology/Oncology, Royal Hospital for Sick Children, and Department of Child Life and Health, University of Edinburgh, Edinburgh, UK.
Ann H PartridgeDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Paola AnseriniPhysiopathology of Human Reproduction, IRCCS AOU San Martino - IST, Genoa, Italy.
Ospedale Policlinico San Martino · ITUniversity of Turin · ITAzienda Ospedaliera S.Giuseppe Moscati · ITClinica Valle Giulia · ITDana-Farber Cancer Institute · USEnte Ospedaliero Ospedali Galliera · ITEuropean Institute of Oncology · ITRoyal Hospital for Children · GBUniversité Libre de Bruxelles · BEUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last years, thanks to the improvement in the prognosis of cancer patients, a growing attention has been given to the fertility issues. International guidelines on fertility preservation in cancer patients recommend that physicians discuss, as early as possible, with all patients of reproductive age their risk of infertility from the disease and/or treatment and their interest in having children after cancer, and help with informed fertility preservation decisions. As recommended by the American Society of Clinical Oncology and the European Society for Medical Oncology, sperm cryopreservation and embryo/oocyte cryopreservation are standard strategies for fertility preservations in male and female patients, respectively; other strategies (e.g. pharmacological protection of the gonads and gonadal tissue cryopreservation) are considered experimental techniques. However, since then, new data have become available, and several issues in this field are still controversial and should be addressed by both patients and their treating physicians.In April 2015, physicians with expertise in the field of fertility preservation in cancer patients from several European countries were invited in Genova (Italy) to participate in a workshop on the topic of "cancer and fertility preservation". A total of ten controversial issues were discussed at the conference. Experts were asked to present an up-to-date review of the literature published on these topics and the presentation of own unpublished data was encouraged. On the basis of the data presented, as well as the expertise of the invited speakers, a total of ten recommendations were discussed and prepared with the aim to help physicians in counseling their young patients interested in fertility preservation.Although there is a great interest in this field, due to the lack of large prospective cohort studies and randomized trials on these topics, the level of evidence is not higher than 3 for most of the recommendations highlighting the need of further research efforts in many areas of this field. The participation to the ongoing registries and prospective studies is crucial to acquire more robust information in order to provide evidence-based recommendations.

Indexed as

Practice Guidelines as TopicAdultChildConsensus Statements as TopicCounselingCryopreservationEuropeExpert TestimonyFemaleFertility PreservationHumansInfertilityInternationalityMaleMedical OncologyNeoplasms

Identifiers

PMID26728489
PMCPMC4700580
OpenAlexW2224634640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.