Evidence map›Paper›PMID 26728486›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2016

Acetazolamide in vestibular migraine prophylaxis: a retrospective study.

Neşe Çelebisoy, Figen Gökçay, Ceyda Karahan, Cem Bilgen, Tayfun Kirazlı, Hale Karapolat, Timur Köse

Abstract read
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Serotonin reuptake inhibiting antidepressants: A trigger for visual snow syndrome?The International journal of risk & safety in medicine · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Recent Trends in Treatment of Vestibular Migraine: A Systematic Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  7. Review
  8. Review
  9. Review
  10. Vestibular migraine: the chameleon in vestibular disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  11. Article
  12. Article
  13. Review
  14. Current Treatment Options: Vestibular Migraine.Current treatment options in neurology · 2017
    Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Neşe ÇelebisoyDepartment of Neurology, Ege University Medical School, Bornova, İzmir, 35100, Turkey. nese.celebisoy@ege.edu.tr.
Figen GökçayDepartment of Neurology, Ege University Medical School, Bornova, İzmir, 35100, Turkey.
Ceyda KarahanDepartment of Otorhinolaryngology, Head and Neck Surgery, Ege University Medical School, Bornova, İzmir, 35100, Turkey.
Cem BilgenDepartment of Otorhinolaryngology, Head and Neck Surgery, Ege University Medical School, Bornova, İzmir, 35100, Turkey.
Tayfun KirazlıDepartment of Otorhinolaryngology, Head and Neck Surgery, Ege University Medical School, Bornova, İzmir, 35100, Turkey.
Hale KarapolatDepartment of Physical Medicine and Rehabilitation, Ege University Medical School, Bornova, İzmir, 35100, Turkey.
Timur KöseDepartment of Biostatistics and Medical Informatics, Ege University Medical School, Bornova, İzmir, 35100, Turkey.
Ege University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to check the efficacy of acetazolamide in the prophylaxis of vestibular migraine (VM). Treatment options in VM are mainly based on migraine guidelines. We tried to assess the efficacy of acetazolamide in these patients depending on clinical similarities with episodic ataxia type 2 and familial hemiplegic migraine responding to the drug. This is a retrospective cohort study. Among 50 patients with VM and prescribed acetazolamide 500 mg/day, 39 patients were studied as five had been lost on follow-up and six had stopped taking the drug due to side effects. Vertigo and headache frequency determined by number of attacks per month, and the severity determined by visual analog scales measured in centimeters from 0 to 10 were collected from the records. Initial reported figures for frequency and severity were compared with the results gathered after 3 months of treatment. The results were compared. Acetazolamide was effective in reducing both the frequency and severity of vertigo and headache attacks and this effect was more prominent for vertigo frequency and severity.

Indexed as

AcetazolamideAdultAgedAnalgesicsFemaleHeadacheHumansMaleMiddle AgedMigraine DisordersPain MeasurementRetrospective StudiesSeverity of Illness IndexVertigoVestibule, LabyrinthAcetazolamideAnalgesicsAcetazolamideProphylaxisVestibular migraine

Identifiers

PMID26728486
OpenAlexW2229687991

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.