Evidence map›Paper›PMID 26728406›Full record

ArticleParasites & vectors2016

Cat scratches, not bites, are associated with unipolar depression--cross-sectional study.

Jaroslav Flegr, Zdeněk Hodný

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Beyond Latency: ChronicBiomedicines · 2025
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  4. Medicina (Kaunas, Lithuania) · 2022
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  6. Examining the Relationship betweenPathogens (Basel, Switzerland) · 2021
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  7. Article
  8. Neurological and Neurobehavioral Disorders Associated withJournal of parasitology research · 2021
    Review
  9. Frontiers in psychiatry · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. BMJ open · 2017
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jaroslav FlegrDepartment of Biology, Faculty of Science, Charles University in Prague, Viničná 7, 128 44, Prague, Czech Republic. flegr@cesnet.cz.
Zdeněk HodnýDepartment of Genome Integrity, Institute of Molecular Genetics ASCR, v.v.i, Prague, Czech Republic. Hodny@img.cas.cz.
Charles University · CZCzech Academy of Sciences, Institute of Molecular Genetics · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA recent study performed on 1.3 million patients showed a strong association between being bitten by a cat and probability of being diagnosed with depression. Authors suggested that infection with cat parasite Toxoplasma could be the reason for this association.

methodA cross sectional internet study on a non-clinical population of 5,535 subjects was undertaken.

resultsThe subjects that reported having been bitten by a dog and a cat or scratched by a cat have higher Beck depression score. They were more likely to have visited psychiatrists, psychotherapists and neurologists in past two years, to have been previously diagnosed with depression (but not with bipolar disorder). Multivariate analysis of models with cat biting, cat scratching, toxoplasmosis, the number of cats at home, and the age of subjects as independent variables showed that only cat scratching had positive effect on depression (p = 0.004). Cat biting and toxoplasmosis had no effect on the depression, and the number of cats at home had a negative effect on depression (p = 0.021).

conclusionsAbsence of association between toxoplasmosis and depression and five times stronger association of depression with cat scratching than with cat biting suggests that the pathogen responsible for mood disorders in animals-injured subjects is probably not the protozoon Toxoplasma gondii but another organism; possibly the agent of cat-scratched disease - the bacteria Bartonella henselae.

Indexed as

AnimalsBartonella henselaeCatsCat-Scratch DiseaseCross-Sectional StudiesDepressionDogsFemaleHumansMaleMultivariate Analysis

Identifiers

PMID26728406
PMCPMC4700762
OpenAlexW2226040036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.