ArticleNature communications2016
HSP90 regulates temperature-dependent seedling growth in Arabidopsis by stabilizing the auxin co-receptor F-box protein TIR1.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 131 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
131 citing papers in PubMed, 274 citations in OpenAlex.
- Nuclear auxin signaling and temperature: perception and response across scales.The New phytologist · 2026Review
- A review of ARGOS-mediated regulation of plant organ size: molecular mechanisms, environmental interactions, and agricultural implications.Functional & integrative genomics · 2026Review
- Protist oxygen-sensing and the role of prolyl hydroxylase-regulation of E3(SCF) ubiquitin ligases.Biochimica et biophysica acta. General subjects · 2026Review
- Development of the HTRF assay to evaluate the auxin-induced binding between TIR1 and IAA7.The New phytologist · 2026Article
- De-repression of protein phosphatase 5 by the chaperone organizer HOP1 activates plant NLR immunity.Nature plants · 2026Article
- AUXIN RESPONSE FACTOR thermostability.Nature communications · 2026Article
- Thermosensory reconfiguration of the auxin transcriptional pathway to drive root cell growth.Nature communications · 2026Article
- Molecular mechanisms and breeding strategies for heat tolerance in vegetable crops under global warming.Horticulture research · 2026Article
- Heat acclimation induces AcLBD1 activated AcHSFA2s mutual amplification cascade for rapid recovery of root vitality and leaf photosynthesis in kiwifruit.Frontiers in plant science · 2026Article
- Glycoregulation of E3(SCF) ubiquitin ligases in unicellular eukaryotes.Glycobiology · 2025Review
- Hormonal regulation of root growth under moderately elevated temperatures.Annals of botany · 2025Review
- Molecular Mechanisms of the Phytohormone-Heat Shock Protein Pathway in Regulating Plant Thermotolerance.Plants (Basel, Switzerland) · 2025Review
- Plant Hormone Stimulation andPlants (Basel, Switzerland) · 2025Article
- Kelch-type F-box protein TaFBK34 improves wheat seedling tolerance to heat stress.BMC biology · 2025Article
- HSP90 differentially stabilizes plant ABCB-type auxin transporters on the plasma membrane.Nature communications · 2025Article
- Environmental Factors, Developmental Genes and Oxidative Stress Determine Inter-Species Variability in Seed Longevity in Salicaceae.Plants (Basel, Switzerland) · 2025Article
- Comparative physiological and transcriptomic analyses identify computationally predicted key genes and regulatory pathways in non-heading Chinese cabbage under heat stress.BMC plant biology · 2025Article
- Research Progress on Responses and Regulatory Mechanisms of Plants Under High Temperature.Current issues in molecular biology · 2025Review
- Genome-Wide Identification and Expression Analysis of the HSP90 Gene Family in Relation to Developmental and Abiotic Stress in Ginger (Plants (Basel, Switzerland) · 2025Article
- Comparative Transcriptome Analysis ofInternational journal of molecular sciences · 2025Article
71 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Recent studies have revealed that a mild increase in environmental temperature stimulates the growth of Arabidopsis seedlings by promoting biosynthesis of the plant hormone auxin. However, little is known about the role of other factors in this process. In this report, we show that increased temperature promotes rapid accumulation of the TIR1 auxin co-receptor, an effect that is dependent on the molecular chaperone HSP90. In addition, we show that HSP90 and the co-chaperone SGT1 each interact with TIR1, confirming that TIR1 is an HSP90 client. Inhibition of HSP90 activity results in degradation of TIR1 and interestingly, defects in a range of auxin-mediated growth processes at lower as well as higher temperatures. Our results indicate that HSP90 and SGT1 integrate temperature and auxin signalling in order to regulate plant growth in a changing environment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.