ArticleParasites & vectors2016
Candidatus Neoehrlichia mikurensis in ticks and rodents from urban and natural habitats of South-Western Slovakia.
Article in Parasites & vectors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- Sympatric Occurrence of Five Exophilic Tick Species in the Levice Region (Southwestern Slovakia) and Their Infection with Tick-Borne Pathogens.Pathogens (Basel, Switzerland) · 2026Article
- From reservoirs to ecological integrators: the role of EuropeanFrontiers in veterinary science · 2026Review
- Pathogen diversity of the neglected winter tickCurrent research in parasitology & vector-borne diseases · 2026Article
- Detection and genetic diversity of Neoehrlichia mikurensis in rodents from central and southern Shanxi, China.Scientific reports · 2025Article
- Molecular Surveillance ofPathogens (Basel, Switzerland) · 2025Article
- Potential drivers of vector-borne pathogens in urban environments: European hedgehogs (One health (Amsterdam, Netherlands) · 2024Article
- The role of wildlife in the epidemiology of tick-borne diseases in Slovakia.Current research in parasitology & vector-borne diseases · 2024Review
- Candidatus Neoehrlichia mikurensis and Hepatozoon sp. in voles (Microtus spp.): occurrence and evidence for vertical transmission.Scientific reports · 2023Article
- Review
- Investigation of Tick-Borne Pathogens inPathogens (Basel, Switzerland) · 2021Article
- Clinical Aspects and Detection of Emerging Rickettsial Pathogens: A "One Health" Approach Study in Serbia, 2020.Frontiers in microbiology · 2021Article
- Comparison of tick-borne pathogen prevalence in Ixodes ricinus ticks collected in urban areas of Europe.Scientific reports · 2020Article
- Highly prevalent bartonellae and other vector-borne pathogens in small mammal species from the Czech Republic and Germany.Parasites & vectors · 2019Article
- Diverse tick-borne microorganisms identified in free-living ungulates in Slovakia.Parasites & vectors · 2018Article
- 'New microbes and new infections · 2018Review
- Prevalence of tick-borne pathogens in questing Ixodes ricinus ticks in urban and suburban areas of Switzerland.Parasites & vectors · 2017Article
- Diversity and prevalence of Bartonella species in small mammals from Slovakia, Central Europe.Parasitology research · 2017Article
- Babesia spp. in ticks and wildlife in different habitat types of Slovakia.Parasites & vectors · 2016Article
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCandidatus Neoehrlichia mikurensis (CNM) is an emerging tick-borne pathogen causing severe disease in immunocompromised patients. In Europe, Ixodes ricinus is the primary vector and rodents act as reservoir hosts. New data on the prevalence of CNM in ticks and rodents contribute to the knowledge on the distribution of endemic areas and circulation of the bacterium in natural foci.
methodsQuesting ticks were collected and rodents were trapped in urban/suburban and natural habitats in South-Western Slovakia from 2011 to 2014. DNA from questing and rodent-attached ticks and rodent tissues were screened for CNM by real-time PCR. Rodent spleen samples positive for CNM were characterised at the groEL gene locus. Spatial and temporal differences in CNM prevalence in ticks and rodents and co-infections of ticks with CNM and Anaplasma phagocytophilum were analysed.
resultsThe presence of CNM was confirmed in questing and rodent-attached I. ricinus ticks and in rodents. Total prevalence in both ticks and rodents was significantly higher in the natural habitat (2.3% and 10.1%, respectively) than in the urban/suburban habitat (1.0% and 3.3%, respectively). No seasonal pattern in CNM prevalence in ticks was observed, but prevalence in rodents was higher in autumn than in spring. CNM was detected in Apodemus flavicollis, Myodes glareolus, Microtus arvalis and Micromys minutus, with the highest prevalence in M. arvalis (30%). By screening CNM dissemination in rodent tissues, infection was detected in lungs of all specimens with positive spleens and in blood, kidney, liver and skin of part of those individuals. Infection with CNM was detected in 1.3% of rodent attached I. ricinus ticks. Sequences of a fragment of the groEL gene from CNM-positive rodents showed a high degree of identity with sequences of the gene amplified from ticks and infected human blood from Europe. Only 0.1% of CNM-positive questing ticks carried A. phagocytophilum. Ticks infected with CNM prevailed in the natural habitat (67.2%), whereas ticks infected with A. phagocytophilum prevailed in the urban/suburban habitat (75.0%).
conclusionThe study confirmed the circulation of CNM between I. ricinus ticks and rodents in South-Western Slovakia, and indicates a potential risk of contracting human infections.
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