ArticleDoklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections2015
The role of nitric oxide in regulation of leukocyte migration into the heart tissue in vitro.
Article in Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Characteristics of leukocyte migration have been studied during the incubation of the right and left ventricles of rat heart explants in autologous blood plasma. Within the first 60 min, the leukocyte amount in the medium increases. Moreover, it is associated with cell release from the heart tissue. During further incubation, the cell release decreases; after 3 h of incubation, the cells begin to migrate back into the heart tissue. However, neutrophil migration does not change. Sodium nitrite, being a donor of nitric oxide significantly, reduces the leukocyte migration from the heart explants into the incubation medium, especially from left ventricle explants.
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