ArticleInternational urology and nephrology2016
Gender-specific association between metabolic syndrome and decreased glomerular filtration rate in elderly population.
Article in International urology and nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Intraoperative Hypertension Is Associated with Postoperative Acute Kidney Injury after Laparoscopic Surgery.Journal of personalized medicine · 2023Article
- Higher neutrophil to lymphocyte ratio is associated with renal dysfunction and cardiac adverse remodeling in elderly with metabolic syndrome.Frontiers in cardiovascular medicine · 2022Article
- Metabolic Syndrome Severity and Risk of CKD and Worsened GFR: The Jackson Heart Study.Kidney & blood pressure research · 2018Article
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFew studies have investigated the association between metabolic syndrome (MS) and chronic kidney disease in the elderly. Accordingly, the aim of this study was to examine the sex-specific association between MS and decreased glomerular filtration rate (GFR) in a Chinese elderly population.
methodsWe performed cross-sectional analyses of older (age ≥60 years) males (n = 19,015) and females (n = 23,310) classified as 0, 1, 2, 3, 4, and 5 component(s) or MS group based on the presenting MS component(s). Sex-specific relationship of decreased GFR with MS component(s) was analyzed by logistic regression models.
resultsCompared with participants with 0 component of MS, males with 1, 2, 3, 4, and 5 component(s) had 1.40-, 1.79-, 2.41-, 3.29-, and 4.09-fold risks for decreased GFR; females with 1, 2, 3, 4, and 5 component(s) had 1.65-, 1.71-, 1.88-, 2.32-, and 1.96-fold risks for decreased GFR, respectively. The multivariate-adjusted odds ratios for decreased GFR in males and females with MS compared with those without MS were 1.79 and 1.25, respectively. For participants without hypertension and diabetes, the association of MS with decreased GFR was still significant.
conclusionsIn this study of 42,325 Chinese participants aged ≥60 years, MS was significantly associated with decreased GFR, and the association was more profound for males than females.
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