SynthesisInternational urology and nephrology2016
Is steroids therapy effective in treating phimosis? A meta-analysis.
Synthesis in International urology and nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Treatment Effects in Randomized and Nonrandomized Studies of Pharmacological Interventions: A Meta-Analysis.JAMA network open · 2024Pooled it
- Topical corticosteroids for treating phimosis in boys.The Cochrane database of systematic reviews · 2024Pooled it
- Effectiveness of low to moderate potency topical corticosteroids for phimosis resolution in children: results of a network meta-analysis.International urology and nephrology · 2025Review
- Phimosis in Adults: Narrative Review of the New Available Devices and the Standard Treatments.Clinics and practice · 2024Review
- Primary care of preputial adhesions in children - a retrospective cohort study.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2022Article
- Can circumcision be avoided in adult male with phimosis? Results of the PhimoStopTranslational andrology and urology · 2021Article
- Topical corticosteroids for phimosis in children: a network meta-analysis of randomized clinical trials.Pediatric surgery international · 2021Article
- Canadian Urological Association guideline on the care of the normal foreskin and neonatal circumcision in Canadian infants (abridged version).Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2018Article
- Article
- Efficacy of Short Duration of Topical Steroids Followed by Adhesiolysis for Management of Preputial Adhesions.Journal of Indian Association of Pediatric SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe evaluated a systematic review on the therapeutic efficacy of topical steroids in children with phimosis to provide data for the clinical options of pediatric phimosis.
methodsWe searched the related original studies on topical steroid therapy in pediatric phimosis before August 2014. Two reviewers independently performed the study selection, data extraction, risk of bias and reporting quality assessment with confirmation by cross-checking. The quality of eligible studies was appraised with the 'Cochrane handbook.' The meta-analysis was performed by REVMAN 5.2 software.
resultsEleven studies were included with 1669 patients among which 1093 received topical steroids and 576 cases treated with placebo or only manual reduction. Significant difference of the treatment efficacy was detected among the three methods [OR 7.46, 95 % CI (4.42, 12.58), p < 0.00001]. In subgroup analysis, significant difference of the treatment efficacy was also detected whether with placebo or manual reduction only [respectively, OR 5.04, 95 % CI (3.19, 7.95), p < 0.00001; OR 16.28, 95 % CI (6.06, 43.69), p < 0.00001].
conclusionsCompared to the placebo or manual reduction method, the topical steroid therapy is more effective in the treatment of phimosis in children. Although there is still controversy in the different type and dosage of steroid, this could be used against phimosis before circumcision.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.