Evidence map›Paper›PMID 26725048›Full record

ArticleBehavior genetics2016

Associations Between Fetal Growth and Self-Perceived Health Throughout Adulthood: A Co-twin Control Study.

Miriam A Mosing, Sven Cnattingius, Margaret Gatz, Jenae M Neiderhiser, Nancy L Pedersen

Open access · greenAbstract readTwin Study
In one paragraph

Article in Behavior genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies - An Update.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2019
    Trial
  2. The Interplay of Genes and Environment Across Multiple Studies (IGEMS) Consortium After Fifteen Years.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2026
    Article
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Miriam A MosingDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden. Miriam.Mosing@ki.se.
Sven CnattingiusClinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.
Margaret GatzDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Jenae M NeiderhiserDepartment of Psychology, The Pennsylvania State University, University Park, PA, USA.
Nancy L PedersenDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Karolinska Institutet · SEPennsylvania State University · USUniversity of Southern California · US

Funding

Gene-Environment Interplay of Social Contexts and Aging-Related OutcomesR01AG037985 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PEDERSEN, NANCY L · 2010 to 2014
$3.2M
Gene-Environment Interplay of Social Contexts and Aging-Related OutcomesR56AG037985 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET, PEDERSEN, NANCY L · 2016 to 2016
$818k
NIA NIH HHS R01 AG037985NIA NIH HHS R56 AG037985
6 · The paper itself

Abstract

The literature shows evidence for long-lasting effects of low birth weight (LBW) on many health outcomes, but little is known about effects on self-perceived health. Findings are mixed and studies are small, mostly focusing on LBW effects on health outcomes before adulthood. Further, as LBW and most health conditions including self-perceived health are partly heritable, associations between birth weight (BW) and adverse health outcomes may also be due to shared genetic as well as other (pre- and postnatal) unmeasured environmental influences. We explored LBW effects on self-perceived health in early and later adulthood using a very large and genetically informative sample of more than 50,000 Swedish twins. In addition, analyses within twin pairs (the co-twin control design) were used to examine potential associations between BW and the offspring's risk for poor self-perceived health independent of shared environmental or genetic factors, evidence which is critical for the understanding of underlying mechanisms. Results showed that lower BW was significantly associated with poorer self-perceived health during adulthood, although the effect size was small. Co-twin control analyses suggested that this increased risk may be due to shared underlying liability (environmental or genetic) rather than a direct effect of BW, but findings were not conclusive.

Indexed as

Fetal DevelopmentHealthSelf ConceptTwinsAdultCohort StudiesFemaleHumansMaleMiddle AgedOdds RatioBirth weightFetal growthSelf-rated healthSubjective healthTwin design

Identifiers

PMID26725048
PMCPMC4860031
OpenAlexW2222453100

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.