Evidence map›Paper›PMID 26724927›Full record

ArticleMagma (New York, N.Y.)2016

In vivo MR spectroscopy of human breast tissue: quantification of fatty acid composition at a clinical field strength (3 T).

Amandine Coum, Lobna Ouldamer, Fanny Noury, Laurent Barantin, Aymeric Saint-Hilaire, Anne Vilde, Philippe Bougnoux, Giulio Gambarota

Abstract read
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In one paragraph

Article in Magma (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
  5. Article
  6. Article
  7. Alteration in lipid composition differentiates breast cancer tissues: aMetabolomics : Official journal of the Metabolomic Society · 2018
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Amandine CoumUniversité de Rennes 1, 35000, Rennes, France. amandine.coum@gmail.com.
Lobna OuldamerDépartement de Gynécologie, CHRU de Tours, 37044, Tours, France.
Fanny NouryUniversité de Rennes 1, 35000, Rennes, France.
Laurent BarantinUniversité François-Rabelais, 37044, Tours, France.
Aymeric Saint-HilaireDépartement de Radiologie, CHRU de Tours, 37044, Tours, France.
Anne VildeDépartement de Radiologie, CHRU de Tours, 37044, Tours, France.
Philippe BougnouxINSERM U1069, 37044, Tours, France.
Giulio GambarotaUniversité de Rennes 1, 35000, Rennes, France.
Centre Hospitalier Universitaire de Tours · FRInserm · FRUniversité de Rennes · FRClinical Investigation Center Plurithematic Tours · FRUniversité de Tours · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the feasibility of in vivo measurement of the fatty acid (FA) composition of breast adipose tissue by MRS on a clinical platform. MATERIAL AND

methodsMRS experiments were performed at 3 T, using a STEAM sequence, on 25 patients diagnosed with breast cancer. MR spectra, acquired on healthy breast tissue, were analysed with the LCModel.

resultsThe measured values of the saturated fatty acid (SFA), mono-unsaturated fatty acid (MUFA) and poly-unsaturated fatty acid (PUFA) fractions were 23.8 ± 7.1%, 55.4 ± 6.8% and 20.8 ± 4.4%, respectively. The values of SFA, MUFA and PUFA observed in the current study are in the same range as those found in two previous studies performed at 7 T.

conclusionThe results of the current study show that it is possible to quantify the fatty acid composition of breast tissue in vivo in a clinical setting (3 T).

Indexed as

Magnetic Resonance SpectroscopyAdipose TissueAgedBiomarkers, TumorBreastFatty AcidsFatty Acids, MonounsaturatedFatty Acids, UnsaturatedFemaleHumansMiddle AgedSoftwareBiomarkers, TumorFatty AcidsFatty Acids, MonounsaturatedFatty Acids, UnsaturatedBreast cancerFatty acidMRSQuantification

Identifiers

PMID26724927
OpenAlexW2222380624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.