Evidence map›Paper›PMID 26724409›Full record

Trial reportUrology2016

Effects of Physiotherapy in the Treatment of Neurogenic Bladder in Patients Infected With Human T-Lymphotropic Virus 1.

Rosana C P Andrade, José A Neto, Luciana Andrade, Tatiane S Oliveira, Dislene N Santos, Cassius J V Oliveira, Márcio J Prado, Edgar M Carvalho

Registry-linked trialOpen access · bronzeAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06616675 (Darifenacin Versus Parasacral Transcutaneous Electric Nerve Stimulation for Overactive Bladder Syndrome in Patients Infected With Human T-Lymphotropic Virus 1 - Randomized Open Clinical Trial), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06616675 phase4completednot on this mapstarted 2022, after this paper: background citation

Darifenacin Versus Parasacral Transcutaneous Electric Nerve Stimulation for Overactive Bladder Syndrome in Patients Infected With Human T-Lymphotropic Virus 1 - Randomized Open Clinical Trial

TypeinterventionalSponsorHospital Universitário Professor Edgard SantosRan2022 to 2023Enrolled42ConditionsHTLV-1, Overactive Bladder SyndromeArmsDarifenacin, Neuromodulation - Sacral nerve stimulation
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Review
  6. Onabotulinumtoxin type A improves lower urinary tract symptoms and quality of life in patients with human T cell lymphotropic virus type 1 associated overactive bladder.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rosana C P AndradePhysiotherapy Department, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia (UFBA), Salvador, Bahia, Brazil; Postgraduate Program in Health Sciences, Federal University of Bahia School of Medicine, Salvador, Bahia, Brazil.
José A NetoImmunology Service, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia (UFBA), Salvador, Bahia, Brazil; Postgraduate Program in Health Sciences, Federal University of Bahia School of Medicine, Salvador, Bahia, Brazil.
Luciana AndradePhysiotherapy Department, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia (UFBA), Salvador, Bahia, Brazil.
Tatiane S OliveiraPhysiotherapy Department, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia (UFBA), Salvador, Bahia, Brazil.
Dislene N SantosPhysiotherapy Department, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia (UFBA), Salvador, Bahia, Brazil.
Cassius J V OliveiraImmunology Service, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia (UFBA), Salvador, Bahia, Brazil; Postgraduate Program in Health Sciences, Federal University of Bahia School of Medicine, Salvador, Bahia, Brazil.
Márcio J PradoDepartment of Gynecology, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia (UFBA), Salvador, Bahia, Brazil.
Edgar M CarvalhoImmunology Service, Complexo Hospitalar Professor Edgard Santos, Universidade Federal da Bahia (UFBA), Salvador, Bahia, Brazil; Gonçalo Moniz Research Center, Fiocruz, Salvador, Bahia, Brazil; National Institute of Science and Technology in Tropical Diseases (INCT-DT), MCT/CNPq, Universidade Federal da Bahia (UFBA), Salvador, Bahia, Brazil; Postgraduate Program in Health Sciences, Federal University of Bahia School of Medicine, Salvador, Bahia, Brazil. Electronic address: edgar@ufba.br.
Universidade Federal da Bahia · BRComplexo Hospitalar Universitário Professor Edgard Santos · BRFundação Oswaldo Cruz · BR

Funding

TROPICAL INFECTIOUS DISEASE TRAINING GRANTD43TW007127 · FIC · FEDERAL UNIVERSITY OF BAHIA · PI CARVALHO, EDGAR M · 2004 to 2009
$733k
FIC NIH HHS D43 TW007127
6 · The paper itself

Abstract

objectiveTo evaluate the efficacy of physiotherapy for urinary manifestations in patients with human T-lymphotropic virus 1-associated lower urinary tract dysfunction.

methodsOpen clinical trial was conducted with 21 patients attending the physiotherapy clinic of the Hospital Universitário, Bahia, Brazil. Combinations of behavioral therapy, perineal exercises, and intravaginal or intra-anal electrical stimulation were used.

resultsThe mean age was 54 ± 12 years and 67% were female. After treatment, there was an improvement in symptoms of urinary urgency, frequency, incontinence, nocturia, and in the sensation of incomplete emptying (P < .001). There was also a reduction in the overactive bladder symptom score from 10 ± 4 to 6 ± 3 (P < .001) and an increase in the perineal muscle strength (P <.001). The urodynamic parameters improved, with reduction in the frequency of patients with detrusor hyperactivity from 57.9% to 42.1%, detrusor-sphincter dyssynergia from 31.6% to 5.3%, detrusor hypocontractility from 15.8% to 0%, and detrusor areflexia from 10.5% to 0%, with positive repercussions in the quality of life in all patients.

conclusionPhysiotherapy was effective in cases of human T-lymphotropic virus 1-associated neurogenic bladder, reducing symptoms, increasing perineal muscle strength, and improving urodynamic parameters and quality of life.

Indexed as

Physical Therapy ModalitiesFemaleHTLV-I InfectionsHumansMaleMiddle AgedUrinary Bladder, Neurogenic

Identifiers

PMID26724409
PMCPMC4792685
OpenAlexW2197384897

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.