Evidence map›Paper›PMID 26722338›Full record

ArticleInternational archives of otorhinolaryngology2016

Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis.

Edmir Américo Lourenço, Eduardo José Caldeira, César Alexandre Fabrega Carvalho, Marcelo Rodriques Cunha, Marcus Vinícius Henriques Carvalho, Saulo Duarte Passos

Open access · diamondAbstract read
In one paragraph

Article in International archives of otorhinolaryngology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 13 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Edmir Américo LourençoDepartment of Otorhinolaryngology, Faculdade de Medicina de Jundiaí, Jundiaí, São Paulo, Brazil.
Eduardo José CaldeiraDepartment of Morphology, Faculdade de Medicina de Jundiaí, Jundiaí, São Paulo, Brazil.
César Alexandre Fabrega CarvalhoDepartment of Morphology, Faculdade de Medicina de Jundiaí, Jundiaí, São Paulo, Brazil.
Marcelo Rodriques CunhaDepartment of Morphology, Faculdade de Medicina de Jundiaí, Jundiaí, São Paulo, Brazil.
Marcus Vinícius Henriques CarvalhoDepartment of Surgery, Faculdade de Medicina de Jundiaí, Jundiaí, São Paulo, Brazil.
Saulo Duarte PassosDepartment of Pediatrics, Faculdade de Medicina de Jundiaí, Jundiaí, São Paulo, Brazil.
Faculdade de Medicina de Jundiaí · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction The relevance of allergic rhinitis is unquestionable. This condition affects people's quality of life and its incidence has increased over the last years. Objective Thus, this study aims to analyze the effectiveness of subcutaneous injectable immunotherapy in cases of nasal itching, sneeze, rhinorrhea and nasal congestion in allergic rhinitis patients. Methods In the present study, the same researcher analyzed the records of 281 patients. Furthermore, the researchers identified allergens through puncture cutaneous tests using standardized extracts containing acari, fungi, pet hair, flower pollen, and feathers. Then, the patients underwent treatment with subcutaneous specific immunotherapy, using four vaccine vials for desensitization, associated with environmental hygiene. The authors analyzed conditions of nasal itching, sneeze, rhinorrhea, and nasal congestion throughout the treatment, and assigned them with a score ranging from zero (0), meaning absence of these symptoms to three (3), for severe cases. The symptoms were statistically compared in the beginning, during, and after treatment. Results In this study, authors analyzed the cases distribution according to age and the evolution of symptomatology according to the scores, comparing all phases of treatment. The average score for the entire population studied was 2.08 before treatment and 0.44 at the end. These results represent an overall improvement of ∼79% in symptomatology of allergic rhinitis in the studied population. Conclusion The subcutaneous immunotherapy as treatment of allergic rhinitis led to a reduction in all symptoms studied, improving the quality of life of patients, proving itself as an important therapeutic tool for these pathological conditions.

Indexed as

allergen immunotherapyallergyhypersensitivityinjectionsrhinitissubcutaneoussymptoms

Identifiers

PMID26722338
PMCPMC4688001
OpenAlexW2288275630

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.