Evidence map›Paper›PMID 26722266›Full record

ArticleOncology letters2015

Successful treatment with lenalidomide of secondary multiple myeloma with extramedullary liver plasmacytoma in a renal transplant recipient: A case report and review of the literature.

Xiaobao Xie, Wei Wu, Yuandong Zhu, Deliang Liu, Weimin Dong, Haiqian Li, Qing Li, Weiying Gu

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiaobao XieDepartment of Hematology, The First People's Hospital of Changzhou (Third Affiliated Hospital of Suzhou University), Changzhou, Jiangsu 213003, P.R. China.
Wei WuDepartment of Hematology, The First People's Hospital of Changzhou (Third Affiliated Hospital of Suzhou University), Changzhou, Jiangsu 213003, P.R. China.
Yuandong ZhuDepartment of Hematology, The First People's Hospital of Changzhou (Third Affiliated Hospital of Suzhou University), Changzhou, Jiangsu 213003, P.R. China.
Deliang LiuDepartment of Hematology, The First People's Hospital of Changzhou (Third Affiliated Hospital of Suzhou University), Changzhou, Jiangsu 213003, P.R. China.
Weimin DongDepartment of Hematology, The First People's Hospital of Changzhou (Third Affiliated Hospital of Suzhou University), Changzhou, Jiangsu 213003, P.R. China.
Haiqian LiDepartment of Hematology, The First People's Hospital of Changzhou (Third Affiliated Hospital of Suzhou University), Changzhou, Jiangsu 213003, P.R. China.
Qing LiDepartment of Pathology, The First People's Hospital of Changzhou (Third Affiliated Hospital of Suzhou University), Changzhou, Jiangsu 213003, P.R. China.
Weiying GuDepartment of Hematology, The First People's Hospital of Changzhou (Third Affiliated Hospital of Suzhou University), Changzhou, Jiangsu 213003, P.R. China.
The First People's Hospital of Changzhou · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) represents a rare form of post-transplantation lymphoproliferative disorder, and the presence of plasma cells in the liver is generally associated with aggressive forms of MM. In the present study, an unusual case of extramedullary plasmacytoma, affecting the liver and vertebrae of a recipient of a renal transplant, is reported. The patient had been previously treated with bortezomib for an MM following renal transplantation, as diagnosed by percutaneous needle biopsy of the hepatic lesion. He was then treated with 5 cycles of RCD regimen (lenalidomide, 25 mg, days 1-21; cyclophosphamide. 50-100 mg, days 1-21; and dexamethasone, 20 mg, days 1, 8, 15 and 22). The patient achieved partial clinical remission without any severe therapy-associated toxicity effects, indicating that lenalidomide is an effective and safe treatment for extramedullary liver plasmacytoma in renal recipients. In conclusion, the present case study indicated that the RCD regimen was effective and safe in the treatment of relapsed and refractory MM.

Indexed as

extramedullary plasmacytomalenalidomidemultiple myelomarenal transplant

Identifiers

PMID26722266
PMCPMC4665712
OpenAlexW2160523094

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.