Evidence map›Paper›PMID 26722243›Full record

ArticleOncology letters2015

A prognosis model for patients with hepatocellular carcinoma and portal vein tumor thrombus following hepatic resection.

Cheng-Zuo Xiao, Wei Wei, Zhi-Xing Guo, Shu-Hong Li, Yong-Fa Zhang, Jia-Hong Wang, Ming Shi, Rong-Ping Guo

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Cheng-Zuo XiaoDepartment of Hepatobiliary Surgery, Cancer Centre of Sun Yat-Sen University, Guangzhou, Guangdong 510060, P.R. China ; State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong 510060, P.R. China ; Department of General Surgery, Shenzhen Shajing Affiliated Hospital of Guangzhou Medical University, Shenzhen, Guangdong 518100, P.R. China.
Wei WeiDepartment of Hepatobiliary Surgery, Cancer Centre of Sun Yat-Sen University, Guangzhou, Guangdong 510060, P.R. China ; State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong 510060, P.R. China.
Zhi-Xing GuoDepartment of Hepatobiliary Surgery, Cancer Centre of Sun Yat-Sen University, Guangzhou, Guangdong 510060, P.R. China ; State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong 510060, P.R. China.
Shu-Hong LiDepartment of Hepatobiliary Surgery, Cancer Centre of Sun Yat-Sen University, Guangzhou, Guangdong 510060, P.R. China ; State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong 510060, P.R. China.
Yong-Fa ZhangDepartment of Hepatobiliary Surgery, Cancer Centre of Sun Yat-Sen University, Guangzhou, Guangdong 510060, P.R. China ; State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong 510060, P.R. China.
Jia-Hong WangDepartment of Hepatobiliary Surgery, Cancer Centre of Sun Yat-Sen University, Guangzhou, Guangdong 510060, P.R. China ; State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong 510060, P.R. China.
Ming ShiDepartment of Hepatobiliary Surgery, Cancer Centre of Sun Yat-Sen University, Guangzhou, Guangdong 510060, P.R. China ; State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong 510060, P.R. China.
Rong-Ping GuoDepartment of Hepatobiliary Surgery, Cancer Centre of Sun Yat-Sen University, Guangzhou, Guangdong 510060, P.R. China ; State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong 510060, P.R. China.
Sun Yat-sen University Cancer Center · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to identify the risk factors influencing the survival of patients with hepatocellular carcinoma (HCC) affected by portal vein tumor thrombus (PVTT), following hepatic resection, and to establish a prognostic model. Between March 2001 and May 2008, 234 cases of HCC with PVTT that underwent hepatic resection were randomly divided into experimental or validation groups. The association between the clinicopathological factors and disease-free survival (DFS) and overall survival (OS) was analyzed, and the significant factors involved were used to establish a prognostic model, which was then validated. Tumor rupture, number of tumors and macroscopic vascular invasion were observed to be independent risk factors of DFS and OS. In the prognostic model, the DFS and OS of low-, medium- and high-risk patients in the experimental group were observed to be significantly different, compared to those in the validation group. In conclusion, the present study established a prognostic model for patients with HCC affected by PVTT following hepatectomy, and demonstrated that the model may be used to guide the treatment of these patients and predict their prognosis.

Indexed as

hepatic resectionhepatocellular carcinomaportal vein tumor thrombusprognosis modelrisk factors

Identifiers

PMID26722243
PMCPMC4665632
OpenAlexW2156224188

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.