ArticleJournal of medical entomology2016
Infection of Immature Ixodes scapularis (Acari: Ixodidae) by Membrane Feeding.
Article in Journal of medical entomology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
24 citing papers in PubMed.
- Current Knowledge on Tick-Borne Encephalitis Virus Interaction with Ticks: Acquisition, Dissemination, and Persistence.Pathogens (Basel, Switzerland) · 2026Review
- Langat Virus Infection Can Be Demonstrated in Both Tick Salivary Glands and Midgut Within 24 Hours of Blood Feeding.Viruses · 2026Article
- Successful completion of the life cycle of Amblyomma variegatum using tick artificial membrane feeding system.Scientific reports · 2025Article
- Differential susceptibility of geographically distinctEmerging microbes & infections · 2024Article
- Ixodes ricinus as potential vector for Usutu virus.PLoS neglected tropical diseases · 2024Article
- Optimization of artificial membrane feeding system for lone star ticks, Amblyomma americanum (Acari: Ixodidae), and experimental infection with Rickettsia amblyommatis (Rickettsiales: Rickettsiaceae).Journal of medical entomology · 2024Article
- A comparison of Illumina and PacBio methods to build tick salivary gland transcriptomes confirms large expression of lipocalins and other salivary protein families that are not represented in available tick genomes.Ticks and tick-borne diseases · 2023Article
- Optimizing tick artificial membrane feeding for Ixodes scapularis.Scientific reports · 2023Article
- Ticks harbor and excrete chronic wasting disease prions.Scientific reports · 2023Article
- Kinetics of tick infection by the relapsing fever spirochete Borrelia hermsii acquired through artificial membrane feeding chambers.Scientific reports · 2022Article
- Evaluating Transmission Paths for Three DifferentMicroorganisms · 2021Article
- Artificial Feeding of All Consecutive Life Stages ofVaccines · 2021Article
- Growth Dynamics and Antibiotic Elimination of Symbiotic Rickettsia buchneri in the Tick Ixodes scapularis (Acari: Ixodidae).Applied and environmental microbiology · 2021Article
- Interactions Between Ticks and Lyme Disease Spirochetes.Current issues in molecular biology · 2021Article
- The identification of tick autophagy-related genes in Ixodes scapularis responding to amino acid starvation.Ticks and tick-borne diseases · 2020Article
- Tripartite Interactions amongPathogens (Basel, Switzerland) · 2020Article
- Uptake and fecal excretion of Coxiella burnetii by Ixodes ricinus and Dermacentor marginatus ticks.Parasites & vectors · 2020Article
- Sharing the Ride:Frontiers in cellular and infection microbiology · 2020Review
- Identification of Lyme borreliae proteins promoting vertebrate host blood-specific spirochete survival in Ixodes scapularis nymphs using artificial feeding chambers.Ticks and tick-borne diseases · 2018Article
- Plasticity in early immune evasion strategies of a bacterial pathogen.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
A reduction in the use of animals in infectious disease research is desirable for animal welfare as well as for simplification and standardization of experiments. An artificial silicone-based membrane-feeding system was adapted for complete engorgement of adult and nymphal Ixodes scapularis Say (Acari: Ixodidae), and for infecting nymphs with pathogenic, tick-borne bacteria. Six wild-type and genetically transformed strains of four species of bacteria were inoculated into sterile bovine blood and fed to ticks. Pathogens were consistently detected in replete nymphs by polymerase chain reaction. Adult ticks that ingested bacteria as nymphs were evaluated for transstadial transmission. Borrelia burgdorferi and Ehrlichia muris-like agent showed high rates of transstadial transmission to adult ticks, whereas Anaplasma phagocytophilum and Rickettsia monacensis demonstrated low rates of transstadial transmission/maintenance. Artificial membrane feeding can be used to routinely maintain nymphal and adult I. scapularis, and infect nymphs with tick-borne pathogens.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.