ArticleJournal of medical entomology2016
A Native Wolbachia Endosymbiont Does Not Limit Dengue Virus Infection in the Mosquito Aedes notoscriptus (Diptera: Culicidae).
Article in Journal of medical entomology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Strain-specific quantification ofFrontiers in insect science · 2025Article
- Review
- The cellular lives of Wolbachia.Nature reviews. Microbiology · 2023Review
- Impact of the microbiome on mosquito-borne diseases.Protein & cell · 2023Review
- Article
- Detection and Establishment of Aedes notoscriptus (Diptera: Culicidae) Mosquitoes in Southern California, United States.Journal of medical entomology · 2022Article
- Releasing incompatible males drives strong suppression across populations of wild andProceedings of the National Academy of Sciences of the United States of America · 2021Article
- The Antiviral Effects of the Symbiont BacteriaFrontiers in immunology · 2020Review
- Lack of influence by endosymbiont Wolbachia on virus titer in the common bed bug, Cimex lectularius.Parasites & vectors · 2019Article
- Curious entanglements: interactions between mosquitoes, their microbiota, and arboviruses.Current opinion in virology · 2019Review
- Infection of anopheline mosquitoes with Wolbachia: Implications for malaria control.PLoS pathogens · 2018Review
- Zika vector transmission risk in temperate Australia: a vector competence study.Virology journal · 2017Article
- Detection of Wolbachia in Aedes albopictus and Their Effects on Chikungunya Virus.The American journal of tropical medicine and hygiene · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The endosymbiotic bacterium Wolbachia pipientis infects many species of insects and has been transinfected into the mosquito Aedes aegypti (L.), the primary vector of dengue virus (DENV). Recently, it has been shown that Wolbachia blocks the replication and transmission of RNA viruses, such as DENV, in a number of mosquito species including Ae. aegypti and Aedes albopictus (Skuse), which is naturally infected with Wolbachia and considered a secondary vector for DENV. The mosquito species Aedes notoscriptus (Skuse) is highly prevalent in Australia, including in areas where DENV outbreaks have been recorded. The mosquito has been implicated in the transmission of Ross River and Barmah Forest viruses, but not DENV. We investigated whether Wolbachia naturally infects this mosquito species and whether it has an impact on the ability of Ae. notoscriptus to transmit DENV. We show, for the first time, that Ae. notoscriptus is naturally infected with a strain of Wolbachia that belongs to supergroup B and is localized only in the ovaries. However, Wolbachia infection in Ae. notoscriptus did not induce resistance to DENV and had no effect on overall DENV infection rate or titer. The presence of a native Wolbachia in Ae. notoscriptus cannot explain why this mosquito is an ineffective vector of DENV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.