ReviewAngiology2016
Definition of Best Medical Treatment in Asymptomatic and Symptomatic Carotid Artery Stenosis.
Review in Angiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PCSK9 Inhibition in Patients With Symptomatic Intracranial Atherosclerosis
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
Who cites it
24 citing papers in PubMed, 73 citations in OpenAlex.
- Modern Management of Asymptomatic Carotid Stenosis: A Meta-Analysis of CREST-2, SPACE-2, and ECST-2.Annals of clinical and translational neurology · 2026Article
- Prevalence of extracranial carotid artery disease in symptomatic peripheral artery disease and implications for long-term outcome.Annals of medicine · 2025Article
- Cerebral pulse oximetry in carotid endarterectomy: an impact study.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Nerolidol-potential Therapeutic Agent for Various Neurological DisordersCurrent pharmaceutical biotechnology · 2025Review
- Carotid Stenosis and Stroke: Medicines, Stents, Surgery-"Wait-and-See" or Protect?Thrombosis and haemostasis · 2024Article
- Brazilian Angiology and Vascular Surgery Society Guidelines for the treatment of extracranial cerebrovascular disease.Jornal vascular brasileiro · 2024Article
- Review
- Impact of Controlling Nutritional Status score on short-term outcomes after carotid endarterectomy: a retrospective cohort study.Journal of Yeungnam medical science · 2023Article
- Study on the Mechanism of Platelet-Released Clusterins Inducing Restenosis after Carotid Endarterectomy by Activating TLR3/NF-Journal of healthcare engineering · 2022Article
- Successful implementation of best medical treatment for patients with asymptomatic carotid artery stenosis within a randomized controlled trial (SPACE-2).Neurological research and practice · 2021Article
- BMI, high-sensitivity C-reactive protein and the conversion from metabolically healthy to unhealthy phenotype in Chinese adults: a cohort study.Public health nutrition · 2021Article
- Prevalence of internal carotid artery stenosis in ambulatory patients presenting for non-emergent percutaneous coronary angiogram in a single Australian centre.Australasian journal of ultrasound in medicine · 2021Article
- Cholesterol, carotid artery disease and stroke: what the vascular specialist needs to know.Annals of translational medicine · 2020Review
- Inflammation of carotid plaques and risk of cerebrovascular events.Annals of translational medicine · 2020Review
- Diagnostic value of miR-186-5p for carotid artery stenosis and its predictive significance for future cerebral ischemic event.Diagnostic pathology · 2020Article
- Prospective study of hemoglobin A1c and incident carotid artery plaque in Chinese adults without diabetes.Cardiovascular diabetology · 2019Article
- Asymptomatic Carotid Stenosis: Intervention or Best Medical Therapy?Current neurology and neuroscience reports · 2018Review
- Ideal Cardiovascular Health Metrics Associated with Reductions in the Risk of Extracranial Carotid Artery Stenosis: a Population-based Cohort Study.Scientific reports · 2018Article
- Apolipoprotein J as a predictive biomarker for restenosis after carotid endarterectomy: a retrospective study.Acta pharmacologica Sinica · 2018Article
- Recent Trends in Neuro-endovascular Treatment for Acute Ischemic Stroke, Cerebral Aneurysms, Carotid Stenosis, and Brain Arteriovenous Malformations.Neurologia medico-chirurgica · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Implementation of best medical treatment (BMT) is the cornerstone of the management of patients with either asymptomatic or symptomatic carotid artery stenosis. We review the literature to define the components of BMT. Smoking cessation, maintaining a healthy body weight, moderate exercise, and a Mediterranean diet are essential lifestyle measures. Moderate alcohol consumption may also be beneficial but recommending it to patients may be hazardous if they consume too much. The importance of lifestyle measures is largely underestimated by both physicians and patients. Blood pressure and diabetes control, antiplatelet agents, and lipid-lowering treatment with statins/ezetimibe comprise the pharmacological components of BMT. Initiation of an intensive regimen of BMT is a sine qua non for patients with carotid artery stenosis whether or not they are offered or undergo an invasive revascularization procedure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.