ArticleJournal of biomedical optics2015
Living cell dry mass measurement using quantitative phase imaging with quadriwave lateral shearing interferometry: an accuracy and sensitivity discussion.
Article in Journal of biomedical optics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
- A transient RNP compartment boosts translation and growth of mammalian oocytes.Science advances · 2026Article
- Halo-free quantitative phase imaging via physics-constrained self-supervised network.Journal of biomedical optics · 2026Article
- Label-free volumetric refractive-index imaging of fibrillar collagen architecture, assembly, and cell-associated remodeling.bioRxiv : the preprint server for biology · 2026Article
- Label-free interferometry platform for drug response profiling of bioprinted tumor organoids at single-organoid resolution.Nature protocols · 2026Review
- A correlative quantitative phase contrast and fluorescence super-resolution microscope for imaging molecules in their cellular context.bioRxiv : the preprint server for biology · 2025Article
- Article
- Sweet Science: Exploring the Impact of Fructose and Glucose on Brown Adipocyte Differentiation Using Optical Diffraction Tomography.Journal of cellular biochemistry · 2025Article
- Pollen and anther morphological variation in rye was shaped by domestication.BMC plant biology · 2025Article
- Rapid mechanical phenotyping of breast cancer cells based on stochastic intracellular fluctuations.iScience · 2024Article
- Transport-of-intensity phase imaging using commercially available confocal microscope.Journal of biomedical optics · 2024Article
- Quantitative phase microscopies: accuracy comparison.Light, science & applications · 2024Review
- Inspiring a convergent engineering approach to measure and model the tissue microenvironment.Heliyon · 2024Review
- Capturing cell morphology dynamics with high temporal resolution using single-shot quantitative phase gradient imaging.Journal of biomedical optics · 2024Article
- Engineering water exchange is a safe and effective method for magnetic resonance imaging in diverse cell types.Journal of biological engineering · 2024Article
- LVING reveals the intracellular structure of cell growth.Scientific reports · 2024Article
- Measuring Drug Response with Single-Cell Growth Rate Quantification.Analytical chemistry · 2023Article
- Engineering water exchange is a safe and effective method for magnetic resonance imaging in diverse cell types.bioRxiv : the preprint server for biology · 2023Article
- Multispectral in-line hologram reconstruction with aberration compensation applied to Gram-stained bacteria microscopy.Scientific reports · 2023Article
- Dry mass photometry of single bacteria using quantitative wavefront microscopy.Biophysical journal · 2023Article
- Comparing the segmentation of quantitative phase images of neurons using convolutional neural networks trained on simulated and augmented imagery.Neurophotonics · 2023Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Single-cell dry mass measurement is used in biology to follow cell cycle, to address effects of drugs, or to investigate cell metabolism. Quantitative phase imaging technique with quadriwave lateral shearing interferometry (QWLSI) allows measuring cell dry mass. The technique is very simple to set up, as it is integrated in a camera-like instrument. It simply plugs onto a standard microscope and uses a white light illumination source. Its working principle is first explained, from image acquisition to automated segmentation algorithm and dry mass quantification. Metrology of the whole process, including its sensitivity, repeatability, reliability, sources of error, over different kinds of samples and under different experimental conditions, is developed. We show that there is no influence of magnification or spatial light coherence on dry mass measurement; effect of defocus is more critical but can be calibrated. As a consequence, QWLSI is a well-suited technique for fast, simple, and reliable cell dry mass study, especially for live cells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.