ArticleJournal of biomedical optics2015
Ultrahigh polarimetric image contrast enhancement for skin cancer diagnosis using InN plasmonic nanoparticles in the terahertz range.
Article in Journal of biomedical optics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Review
- Terahertz Mie scattering in tissue: diffuse polarimetric imaging and Monte Carlo validation in highly attenuating media models.Journal of biomedical optics · 2025Article
- Recent trends and impact of localized surface plasmon resonance (LSPR) and surface-enhanced Raman spectroscopy (SERS) in modern analysis.Journal of pharmaceutical analysis · 2024Review
- Polarimetry terahertz imaging of human breast cancer surgical specimens.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Terahertz polarimetric imaging of biological tissue: Monte Carlo modeling of signal contrast mechanisms due to Mie scattering.Biomedical optics express · 2024Article
- Terahertz polarimetric imaging of biological tissues: Monte Carlo modeling of signal contrast mechanisms due to Mie scattering.Research square · 2023Article
- Recent Advances and Implication of Bioengineered Nanomaterials in Cancer Theranostics.Medicina (Kaunas, Lithuania) · 2021Review
- Computational absorption and reflection studies of normal human skin at 0.45 THz.Biomedical optics express · 2020Article
- The medical application of terahertz technology in non-invasive detection of cells and tissues: opportunities and challenges.RSC advances · 2019Review
- Skin cancer detection using non-invasive techniques.RSC advances · 2018Review
- A Phantom Study of Terahertz Spectroscopy and Imaging of Micro- and Nano-diamonds and Nano-onions as Contrast Agents for Breast Cancer.Biomedical physics & engineering express · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
Mueller matrix imaging sensitivity, to delicate water content changes in tissue associated with early stages of skin cancer, is demonstrated by numerical modeling to be enhanced by localized surface plasmon resonance (LSPR) effects at the terahertz (THz) range when InN nanoparticles (NPs) coated with Parylene-C are introduced into the skin. A skin tissue model tailored for THz wavelengths is established for a Monte Carlo simulation of polarized light propagation and scattering, and a comparative study based on simulated Mueller matrices is presented considering different NPs’ parameters and insertion into the skin methods. The insertion of NPs presenting LSPR in the THz is demonstrated to enable the application of polarization-based sample characterization techniques adopted from the scattering dominated visible wavelengths domain for the, otherwise, relatively low scattering THz domain, where such approach is irrelevant without the NPs. Through these Mueller polarimetry techniques, the detection of water content variations in the tissue is made possible and with high sensitivity. This study yields a limit of detection down to 0.0018% for relative changes in the water content based on linear degree of polarization--an improvement of an order of magnitude relative to the limit of detection without NPs calculated in a previous ellipsometric study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.