ArticleInvestigative ophthalmology & visual science2015
Location of Initial Visual Field Defects in Glaucoma and Their Modes of Deterioration.
Article in Investigative ophthalmology & visual science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 46 citations in OpenAlex.
- Eye-tracking biomarkers for glaucoma based on saccadic reaction time: a controlled clinical study.Frontiers in ophthalmology · 2025Trial
- Prediction of repeatable glaucomatous visual field defects based on cluster characteristics.The British journal of ophthalmology · 2025Article
- Characterization of the Most Resistant and Vulnerable Retinal Ganglion Cell Subtypes in a Chronic Model of Glaucoma in Rat.Investigative ophthalmology & visual science · 2025Article
- Reliability of Binocular Esterman Visual Field Test in Patients with Glaucoma and Other Ocular Conditions.Diagnostics (Basel, Switzerland) · 2024Article
- Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank.Nature communications · 2023Article
- Despite Impaired Binocular Function, Binocular Disparity Integration Across the Visual Field Is Spared in Normal Aging and Glaucoma.Investigative ophthalmology & visual science · 2023Article
- Detecting disease progression in mild, moderate and severe glaucoma.Current opinion in ophthalmology · 2023Review
- The Relationship between Intracranial Pressure and Visual Field Zones in Normal-Tension Glaucoma Patients.Diagnostics (Basel, Switzerland) · 2023Article
- Cohort Study of Race/Ethnicity and Incident Primary Open-Angle Glaucoma Characterized by Autonomously Determined Visual Field Loss Patterns.Translational vision science & technology · 2022Article
- Anatomic and refractional correlations in earliest glaucomatous visual field defects.Arquivos brasileiros de oftalmologia · 2022Article
- Virtual Reality-Based and Conventional Visual Field Examination Comparison in Healthy and Glaucoma Patients.Translational vision science & technology · 2021Article
- Article
- Binocular Interactions in Glaucoma Patients With Nonoverlapping Visual Field Defects: Contrast Summation, Rivalry, and Phase Combination.Investigative ophthalmology & visual science · 2021Article
- Vision Impairment Provides New Insight Into Self-Motion Perception.Investigative ophthalmology & visual science · 2021Article
- Enhanced Physiological Stress Response in Patients with Normal Tension Glaucoma during Hypoxia.Journal of ophthalmology · 2021Article
- Factors Related to Superior and Inferior Hemifield Defects in Primary Open-Angle Glaucoma.Journal of ophthalmology · 2019Article
- Imaging Retinal Ganglion Cell Death and Dysfunction in Glaucoma.International ophthalmology clinics · 2019Review
- Review
- Annexins in Glaucoma.International journal of molecular sciences · 2018Review
- Application of Pattern Recognition Analysis to Optimize Hemifield Asymmetry Patterns for Early Detection of Glaucoma.Translational vision science & technology · 2018Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
purposeTo describe the location of initial visual field defects (VFD) in glaucoma, their modes of deterioration, and those factors associated with different modes of deterioration.
methodsPatients with POAG were categorized into four groups based on three consecutive initial VFD: (1) superior paracentral defects (PD), (2) inferior PD, (3) superior nasal defects (ND), and (4) inferior ND. According to the worsening of the VF, four further subgroups were identified: (1) superior central worsening (CW), (2) inferior CW, (3) superior peripheral or nasal worsening (NW), and (4) inferior NW. Systemic and ocular factors were analyzed for each of the subgroups to identify possible associations.
resultsOne hundred sixty-two eyes of 162 subjects were analyzed. Superior PD (n = 40) were more frequent in females and associated with disc hemorrhage (DH), and were less frequent in patients with systemic hypertension (HT). Inferior PD (n = 35) showed a significant association with cup shape measure and axial length. Superior ND (n = 37) were more highly associated with HT and diabetes. Inferior ND (n = 50) showed a lower incidence of DH. With binary logistic regression analysis, superior PD showed a significant association with both HT and DH. With respect to VF worsening, superior CW showed a significant association with HT and diabetes, whereas superior NW was associated with a high minimum IOP during follow-up, and inferior NW was associated with a high maximum IOP during follow-up.
conclusionsThe initial location and subsequent direction of worsening of VFD were associated with different systemic and ocular factors.
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Registered trials
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