Evidence map›Paper›PMID 26719955›Full record

Trial reportOtology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology2016

Results of Postoperative, CT-based, Electrode Deactivation on Hearing in Prelingually Deafened Adult Cochlear Implant Recipients.

Robert F Labadie, Jack H Noble, Andrea J Hedley-Williams, Linsey W Sunderhaus, Benoit M Dawant, René H Gifford

Abstract readClinical Trial
In one paragraph

Trial report in Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Cochlear Implant Electrode Placement and Music Perception.JAMA otolaryngology-- head & neck surgery · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Cochlear Implant Research and Development in the Twenty-first Century: A Critical Update.Journal of the Association for Research in Otolaryngology : JARO · 2021
    Review
  7. Auditory performance of post-lingually deafened adult cochlear implant recipients using electrode deactivation based on postoperative cone beam CT images.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Temporal Modulation Detection Depends on Sharpness of Spatial Tuning.Journal of the Association for Research in Otolaryngology : JARO · 2018
    Article
  13. Article
  14. Automatic Detection of the Inner Ears in Head CT Images Using Deep Convolutional Neural Networks.Proceedings of SPIE--the International Society for Optical Engineering · 2018
    Article
  15. Article
  16. Measuring Cochlear Duct Length - a historical analysis of methods and results.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2017
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Robert F Labadie*Department of Otolaryngology-Head and Neck Surgery †Department of Electrical Engineering and Computer Science ‡Department of Hearing and Speech Sciences, Vanderbilt University, Nashville, Tennessee, U.S.A.
Jack H Noble
Andrea J Hedley-Williams
Linsey W Sunderhaus
Benoit M Dawant
René H Gifford
Vanderbilt University · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Research Supplements to Promote Diversity in Health-Related ResearchR01DC008408 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI LABADIE, ROBERT F · 2007 to 2022
$7.6M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
Model-based Cochlear Implant ProgrammingR01DC014037 · NIDCD · VANDERBILT UNIVERSITY · PI NOBLE, JACK · 2014 to 2024
$5.0M
Cochlear Implants: Combined Electric and Binaural Acoustic StimulationR01DC009404 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GIFFORD, RENE H · 2010 to 2019
$3.4M
Clinical Application of Spectral Envelope Perception: Cochlear Implant EvaluationR01DC013117 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GIFFORD, RENE H · 2013 to 2017
$1.6M
Image-based frequency reallocation for optimizing cochlear implant programmingR21DC012620 · NIDCD · VANDERBILT UNIVERSITY · PI NOBLE, JACK · 2012 to 2013
$408k
NCATS NIH HHS UL1 TR000445NCATS NIH HHS UL1TR000445NICHD NIH HHS U54 HD083211NIDCD NIH HHS R01 DC008408NIDCD NIH HHS R01DC008408NIDCD NIH HHS R01 DC009404NIDCD NIH HHS R01DC009404NIDCD NIH HHS R01 DC013117NIDCD NIH HHS R01 DC014037NIDCD NIH HHS R21 DC012620NIDCD NIH HHS R21DC012620
6 · The paper itself

Abstract

objectiveTo test the use of a novel, image-guided cochlear implant (CI) programming (IGCIP) technique on prelingually deafened, adult CI recipients. STUDY

designProspective unblinded study.

settingTertiary referral center. PATIENTS: Twenty-six prelingually deafened adult CI recipients with 29 CIs (3 bilateral). INTERVENTION(S): Temporal-bone CT scans were used as input to a series of semiautomated computer algorithms which estimate the location of electrodes in reference to the modiolus. This information was used to selectively deactivate suboptimally located electrodes, i.e., those for which the distance from the electrode to the modiolus was further than a neighboring electrode to the same site. Patients used the new IGCIP program exclusively for 3-5 weeks. MAIN OUTCOME MEASURE(S): Minimum Speech Test Battery (MSTB), quality of life (QOL), and spectral modulation detection (SMD).

resultsOn average one-third of electrodes were deactivated. At the group level, no significant differences were noted for MSTB measures nor for QOL estimates. Average SMD significantly improved after IGCIP reprogramming, which is consistent with improved spatial selectivity. Using 95% confidence interval data for CNC, AzBio, and BKB-SIN at the individual level, 76 to 90% of subjects demonstrated equivocal or significant improvement. Ultimately 21 of 29 (72.41%) elected to keep the IGCIP map because of perceived benefit often substantiated by improvement on either MSTB, QOL, and/or SMD.

conclusionsKnowledge of the geometric relationship between CI electrodes and the modiolus appears to be useful in adjusting CI maps in prelingually deafened adults. Long-term improvements may be observed resulting from improved spatial selectivity and spectral resolution.

Indexed as

Cochlear ImplantsHearingAdultAgedAlgorithmsBrain MappingCochlear ImplantationDeafnessFemaleHumansImage Interpretation, Computer-AssistedMaleMiddle AgedPostoperative PeriodProspective StudiesSpeech Discrimination Tests

Identifiers

PMID26719955
PMCPMC4712086
OpenAlexW2434210320

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.