Evidence map›Paper›PMID 26719892›Full record

ReviewPLoS pathogens2015

Cystic Fibrosis Lung Infections: Polymicrobial, Complex, and Hard to Treat.

Laura M Filkins, George A O'Toole

Abstract readReview
In one paragraph

Review in PLoS pathogens, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Understanding bacterial biofilms: From definition to treatment strategies.Frontiers in cellular and infection microbiology · 2023
    Pooled it
  2. Trial
  3. Review
  4. Copper-driven mutualism ofMicrobiology (Reading, England) · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Interplay ofVirulence · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Ceftobiprole in cystic fibrosis: a case series.JAC-antimicrobial resistance · 2025
    Article
  18. Article
  19. Article
  20. Article

67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Laura M FilkinsDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.
George A O'TooleDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.

Funding

cdiGMP regulation of Biofilm FormationR37AI083256 · NIAID · DARTMOUTH COLLEGE · PI O'TOOLE, GEORGE A. · 2014 to 2023
$4.7M
RENAL FUNCTION AND DISEASET32DK007301 · NIDDK · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 1986 to 2014
$2.3M
cdiGMP regulation of Biofilm FormationR01AI083256 · NIAID · DARTMOUTH COLLEGE · PI O'TOOLE, GEORGE A. · 2009 to 2013
$1.9M
NIAID NIH HHS R01 2 R37 AI83256-06NIAID NIH HHS R37 AI083256NIDDK NIH HHS T32 DK007301
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsCoinfectionCystic FibrosisHumansRespiratory Tract InfectionsAnti-Bacterial Agents

Identifiers

PMID26719892
PMCPMC4700991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.