Evidence map›Paper›PMID 26719792›Full record

ArticleIrish veterinary journal2015

Phylogenetic investigation of enteric bovine coronavirus in Ireland reveals partitioning between European and global strains.

L Gunn, P J Collins, M J O'Connell, H O'Shea

Open access · goldAbstract read
In one paragraph

Article in Irish veterinary journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Bovine Coronavirus and the Associated Diseases.Frontiers in veterinary science · 2021
    Review
  7. Article
  8. Bovine coronavirus in neonatal calf diarrhoea in Iran.Veterinary medicine and science · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Genetic diversity of BCoV in Brazilian cattle herds.Veterinary medicine and science · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

L GunnDepartment of Biological Sciences, Cork Institute of Technology, Rossa Ave, Bishopstown, Cork Ireland.
P J CollinsDepartment of Biological Sciences, Cork Institute of Technology, Rossa Ave, Bishopstown, Cork Ireland.
M J O'ConnellBioinformatics and Molecular Evolution Group, School of Biotechnology, Dublin City University, Glasnevin, Dublin 9 Ireland.
H O'SheaDepartment of Biological Sciences, Cork Institute of Technology, Rossa Ave, Bishopstown, Cork Ireland.
Munster Technological University · IEDublin City University · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBovine coronavirus is a primary cause of neonatal calf diarrhea worldwide, and is also associated with acute diarrhea in adult cattle during the winter season. There are no reports on molecular characterization of bovine coronavirus in Ireland, and little data exists apart from serological studies.

findingsIn this study, 11 neonatal (mean age 9 days) calf BCoV strains from the south of Ireland were collected over a one year period and characterized using molecular methods. The spike gene which encodes a protein involved in viral entry, infectivity and immune response shows the most variability amongst the isolates and was subsequently selected for in depth analysis. Phylogenetic analysis of the spike gene revealed that the Irish strains clustered with novel BCoV strains from Europe in a unique clade, possibly indicating lineage partitioning. Direct analysis of alignments identified amino acid changes in the spike protein unique to the Irish clade.

conclusionThus, monitoring of bovine coronavirus in Ireland is important as the current isolates in circulation in the south of Ireland may be diverging from the available vaccine strain, which may have implications regarding future BCoV vaccine efficacy.

Indexed as

Bovine coronavirusSequence analysisSpike protein

Identifiers

PMID26719792
PMCPMC4696222
OpenAlexW2218048078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.