Evidence map›Paper›PMID 26719717›Full record

ArticleClinicoEconomics and outcomes research : CEOR2016

Cost-effectiveness of minimally invasive sacroiliac joint fusion.

Daniel J Cher, Melissa A Frasco, Renée Jg Arnold, David W Polly

Erratum issued Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in ClinicoEconomics and outcomes research : CEOR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT01681004 (INSITE Investigation of Sacroiliac Fusion Treatment), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01681004 nacompletednot on this map

INSITE Investigation of Sacroiliac Fusion Treatment

TypeinterventionalSponsorSI-BONE, Inc.Ran2012 to 2017Enrolled159ConditionsDegenerative Sacroiliitis, Sacroiliac Joint DisruptionArmsiFuse Implant System, Non-surgical management
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Utility of minimally invasive percutaneous arthrodesis of the sacroiliac joint for the treatment of low back pain: systematic review of the literature.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Pooled it
  2. Article
  3. Article
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  7. [Minimally invasive arthrodesis of the sacroiliac joint (SIJ)].Operative Orthopadie und Traumatologie · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Minimally Invasive Sacroiliac Joint Fusion: The Current Evidence.International journal of spine surgery · 2020
    Article
  14. Economic Value in Minimally Invasive Spine Surgery.Current reviews in musculoskeletal medicine · 2019
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Work intensity in sacroiliac joint fusion and lumbar microdiscectomy.ClinicoEconomics and outcomes research : CEOR · 2016
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Daniel J CherClinical Affairs, SI-BONE, Inc., San Jose, CA, USA.
Melissa A FrascoDivision of Health Economics and Outcomes Research, Quorum Consulting, Inc., San Francisco, CA, USA.
Renée Jg ArnoldDivision of Health Economics and Outcomes Research, Quorum Consulting, Inc., San Francisco, CA, USA ; Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
David W PollyDepartment of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, USA ; Department of Neurosurgery, University of Minnesota, Minneapolis, MN, USA.
Icahn School of Medicine at Mount Sinai · USSI-Bone (United States) · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSacroiliac joint (SIJ) disorders are common in patients with chronic lower back pain. Minimally invasive surgical options have been shown to be effective for the treatment of chronic SIJ dysfunction.

objectiveTo determine the cost-effectiveness of minimally invasive SIJ fusion.

methodsData from two prospective, multicenter, clinical trials were used to inform a Markov process cost-utility model to evaluate cumulative 5-year health quality and costs after minimally invasive SIJ fusion using triangular titanium implants or non-surgical treatment. The analysis was performed from a third-party perspective. The model specifically incorporated variation in resource utilization observed in the randomized trial. Multiple one-way and probabilistic sensitivity analyses were performed.

resultsSIJ fusion was associated with a gain of approximately 0.74 quality-adjusted life years (QALYs) at a cost of US$13,313 per QALY gained. In multiple one-way sensitivity analyses all scenarios resulted in an incremental cost-effectiveness ratio (ICER) <$26,000/QALY. Probabilistic analyses showed a high degree of certainty that the maximum ICER for SIJ fusion was less than commonly selected thresholds for acceptability (mean ICER =$13,687, 95% confidence interval $5,162-$28,085). SIJ fusion provided potential cost savings per QALY gained compared to non-surgical treatment after a treatment horizon of greater than 13 years.

conclusionCompared to traditional non-surgical treatments, SIJ fusion is a cost-effective, and, in the long term, cost-saving strategy for the treatment of SIJ dysfunction due to degenerative sacroiliitis or SIJ disruption.

Indexed as

cost-effectiveness analysisdegenerative sacroiliitisminimally invasive surgerysacroiliac joint arthrodesissacroiliac joint disruptionssacroiliac joint dysfunctionspine surgery

Identifiers

PMID26719717
PMCPMC4690648
OpenAlexW2215596107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.