Evidence map›Paper›PMID 26719639›Full record

ArticleAnnals of dermatology2015

Evaluation of Arterial Stiffness in Patients with Behçet's Disease by Using Noninvasive Radiological Methods such as Intima-Media Thickness of the Carotid, Ankle-Brachial Pressure Index, Coronary Artery Calcium Scoring, and Their Relation to Serum Fetuin-A Levels: A Case-Control Study.

Belkız Uyar, Aynur Solak, Berhan Genç, Muhittin Akyıldız, Neslin Şahin, İhsan Sami Uyar, Ali Saklamaz

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of dermatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Carotid artery stiffness in Behçet's disease.European journal of rheumatology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Belkız UyarDepartment of Dermatology, Faculty of Medicine, Sifa University, Izmir, Turkey.
Aynur SolakDepartment of Radiology, Faculty of Medicine, Sifa University, Izmir, Turkey.
Berhan GençDepartment of Radiology, Faculty of Medicine, Sifa University, Izmir, Turkey.
Muhittin AkyıldızDepartment of Biochemistry, Faculty of Medicine, Sifa University, Izmir, Turkey.
Neslin ŞahinDepartment of Radiology, Faculty of Medicine, Sifa University, Izmir, Turkey.
İhsan Sami UyarDepartment of Cardiovascular Surgery, Faculty of Medicine, Sifa University, Izmir, Turkey.
Ali SaklamazDepartment of Endocrinology, Faculty of Medicine, Sifa University, Izmir, Turkey.
Şifa University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBehçet's disease (BD) is a chronic, recurrent inflammatory systemic vasculitis. Evidence for increased atherosclerosis in BD has been observed. The relation between cardiovascular risk factors and increased atherosclerosis in patients with BD is still controversial.

objectiveWe performed this study to evaluate arterial stiffness in patients with BD by using noninvasive radiological methods such as carotid artery intima-media thickness (CIMT), ankle-brachial pressure index (ABPI), coronary artery calcium score (CACaS), and their relation to serum fetuin-A levels, which was recently found to be important in vascular calcification.

methodsThis prospective study included 26 patients with BD and 25 control subjects. In all patients, the CIMT, ABPI, CACaS, and serum fetuin-A levels were examined.

resultsThe CIMT and CACaS were statistically higher and the ABPI was statistically lower in BD patients than in the control group. All p-values were <0.001. Positive correlations were found between the CACaS and CIMT, and negative correlations were found between the CACaS and ABPI. Although the values of fetuin-A were higher in BD, the difference was not statistically significant (p=0.064). However, the correlations found between fetuin-A levels and CIMT and between fetuin-A levels and CACaS were significant.

conclusionThe CIMT, CACaS, and ABPI are all useful in detecting structural and functional vascular damage in BD.

Indexed as

Alpha-2-HS-GlycoproteinAnkle brachial indexBehçet's diseaseCardiovascular diseasesCarotid intima-media thickness

Identifiers

PMID26719639
PMCPMC4695422
OpenAlexW2340973499

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.